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下肢关节炎患者行腰椎融合术后健康相关生活质量的改善

Health-related quality-of-life improvement with lumbar fusion in patients with lower-extremity arthritis.

作者信息

Djurasovic Mladen, Glassman Steven, Gum Jeffrey L, Crawford Charles H, Owens R Kirk, Carreon Leah Y

出版信息

J Neurosurg Spine. 2020 Sep 4;34(1):60-65. doi: 10.3171/2020.6.SPINE20759. Print 2021 Jan 1.

Abstract

OBJECTIVE

Lumbar fusion can lead to significant improvements in patient-reported outcomes (PROs) in patients with degenerative conditions. It is unknown whether the presence of hip or knee arthritis confounds the responses of patients to low-back-specific PROs. This study examined PROs with lumbar fusion in patients with concomitant lower-extremity arthritis. The purpose of the current study was to examine whether patients with significant lower-extremity arthritis who undergo lumbar fusion achieve similar improvements in low-back-specific PROs compared to patients without lower-extremity arthritis.

METHODS

Patients were identified from a prospectively enrolled multicenter registry of patients undergoing lumbar fusion surgery for degenerative conditions. Two hundred thirty patients identified with lumbar fusion and who also had concomitant lower-extremity arthritis were propensity matched to 233 patients who did not have lower-extremity arthritis based on age, BMI, sex, smoking status, American Society of Anesthesiologists grade, number of levels fused, and surgical approach. One-year improvement in PROs, numeric rating scales (0-10) for back and leg pain, and the Oswestry Disability Index and EuroQol-5D scores were compared for patients with and without lower-extremity arthritis.

RESULTS

Baseline demographics and preoperative outcome measures did not differ between the two propensity-matched groups with 110 cases each. Patients with concomitant lower-extremity arthritis achieved similar improvement in health-related quality-of-life measures to patients without lower-extremity arthritis, with no significant differences between the groups (p > 0.10).

CONCLUSIONS

The presence of lower-extremity arthritis does not adversely affect the results of lumbar fusion in properly selected patients. Patients with lower-extremity arthritis who undergo lumbar fusion can achieve meaningful improvement in PROs similar to patients without arthritis.

摘要

目的

腰椎融合术可显著改善患有退行性疾病患者的患者报告结局(PROs)。目前尚不清楚髋关节炎或膝关节炎的存在是否会混淆患者对下背部特异性PROs的反应。本研究调查了伴有下肢关节炎患者接受腰椎融合术的PROs。本研究的目的是检查与无下肢关节炎的患者相比,患有严重下肢关节炎且接受腰椎融合术的患者在下背部特异性PROs方面是否能取得类似的改善。

方法

从一个前瞻性登记的多中心退行性疾病腰椎融合手术患者队列中识别患者。230例接受腰椎融合术且伴有下肢关节炎的患者根据年龄、体重指数、性别、吸烟状况、美国麻醉医师协会分级、融合节段数和手术方式,与233例无下肢关节炎的患者进行倾向匹配。比较了有和无下肢关节炎患者在PROs方面的一年改善情况、背部和腿部疼痛的数字评分量表(0-10)、Oswestry功能障碍指数和欧洲五维健康量表得分。

结果

两个倾向匹配组各有110例患者,其基线人口统计学和术前结局指标无差异。伴有下肢关节炎的患者在健康相关生活质量指标方面取得了与无下肢关节炎患者相似的改善,两组之间无显著差异(p>0.10)。

结论

在经过适当选择的患者中,下肢关节炎的存在不会对腰椎融合术的结果产生不利影响。接受腰椎融合术的下肢关节炎患者在PROs方面可取得与无关节炎患者类似的有意义的改善。

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