成人颈椎软骨肉瘤伴 Wilms 瘤病史。
Cervical Spine Chondrosarcoma in an Adult with a History of Wilms Tumor.
机构信息
Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Neurosurgery Department, Cairo University, Cairo, Egypt.
出版信息
World Neurosurg. 2020 Dec;144:117-120. doi: 10.1016/j.wneu.2020.08.192. Epub 2020 Sep 2.
INTRODUCTION
We report the first case of cervical spine chondrosarcoma in a Wilms tumor survivor.
CASE DESCRIPTION
A 52-year-old female patient presented with myelopathic symptoms including poor balance, difficulty walking, and numbness of both feet. A magnetic resonance imaging of the spine showed a mass at the right C7-T1 foramen causing significant cord compression. The patient's symptoms improved after posterior decompression and fusion with excision of the tumor.
CONCLUSION
Through our experience with this case, we would like to suggest a possible unknown genetic syndrome predisposing patients with Wilms tumor to chondrosarcoma as secondary neoplasms. We would also like to re-emphasize the need for vigilance when assessing patients with a history of Wilms tumor.
介绍
我们报告了首例威尔姆斯瘤幸存者的颈椎软骨肉瘤病例。
病例描述
一名 52 岁女性患者出现了脊髓病症状，包括平衡不良、行走困难和双脚麻木。脊柱磁共振成像显示右侧 C7-T1 孔有一个肿块，导致脊髓严重受压。患者的症状在接受后路减压和肿瘤切除融合后得到了改善。
结论
通过我们对这个病例的经验，我们建议可能存在一种未知的遗传综合征，使威尔姆斯瘤患者易患软骨肉瘤作为继发肿瘤。我们还想再次强调，在评估有威尔姆斯瘤病史的患者时，需要保持警惕。
Zotero 插件