Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
World Neurosurg. 2021 Jan;145:178-182. doi: 10.1016/j.wneu.2020.08.193. Epub 2020 Sep 2.
Rheumatoid arthritis (RA) is a chronic inflammatory polyarthropathy that affects many synovial joints favoring the hands, knees, and vertebral articulations. Joint laxity manifests as subaxial instability, atlantoaxial instability, and cranial settling (CS).
A 70-year-old woman with past medical history of RA, Hashimoto's thyroiditis, osteoporosis, history of C1-2 fusion for instability 15 years prior, with subsequent revision cervicothoracic fusion for degeneration, and trauma 2 years prior presents with new onset headache, nausea, and vomiting of 36-hour duration. Neurologic examination was only notable for mild right dysmetria. Workup revealed acute hemorrhage in the posterior fossa with migration of the right rod implant and screw tulip, as a result of CS. The patient underwent occipital-cervical fusion with removal of the migratory hardware.
Intracranial rod migration and hemorrhage secondary to CS is a rare complication that must be brought to the attention of surgeons operating on patients with RA.
类风湿关节炎(RA)是一种慢性炎症性多关节炎,影响许多滑膜关节,手部、膝盖和脊椎关节是常见发病部位。关节松弛表现为下颈椎不稳定、寰枢椎不稳定和颅底沉降(CS)。
一名 70 岁女性,既往有 RA、桥本甲状腺炎、骨质疏松症病史,15 年前因不稳定行 C1-2 融合,随后行颈胸段融合以治疗退行性变,2 年前因创伤就诊。现出现新发头痛、恶心和呕吐 36 小时。神经系统检查仅发现右侧运动失调轻微。检查显示颅后窝急性出血,右侧杆状植入物和螺钉郁金香迁移,这是 CS 的结果。患者接受枕颈融合术,同时取出迁移的硬件。
CS 引起的颅内杆状迁移和出血是一种罕见的并发症,必须引起为 RA 患者手术的外科医生的注意。