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阿片类药物使用障碍和创伤住院患者中丁丙诺啡治疗的成功参与。

Successful engagement in buprenorphine treatment among hospitalized patients with opioid use disorder and trauma.

机构信息

Division of General Internal Medicine, University of Washington, Seattle, WA, United States.

University of Washington School of Public Health, Seattle, WA, United States.

出版信息

Drug Alcohol Depend. 2020 Oct 1;215:108253. doi: 10.1016/j.drugalcdep.2020.108253. Epub 2020 Aug 27.

Abstract

BACKGROUND

The opioid epidemic continues to cause significant morbidity and mortality. Although there are effective medications for opioid use disorder (OUD), a minority of patients receive these treatments. OUD is common among patients hospitalized for traumatic injury and hospitalization could be an opportunity to initiate medications and link to ongoing buprenorphine care.

METHODS

This retrospective cohort study based on electronic health record review included patients who were: (1) hospitalized between January 1, 2018 and June 30, 2019, (2) age ≥18 years, (3) seen by an Addiction Medicine Consult Service, and (4) initiated on buprenorphine with plans for continuation post-discharge. Descriptive statistics identified differences between trauma and non-trauma groups and regression analysis identified predictors of 30 day buprenorphine follow up.

RESULTS

Of 197 eligible patients, 60 (30.5 %) were hospitalized for traumatic injuries. Compared to non-trauma patients, trauma patients were younger, more likely to be employed, more likely to report using cannabis and tobacco, less likely to have recently injected drugs, and hospitalized longer. Among patients with follow-up data available (n = 147), 63.2 % of trauma patients were seen within 30 days, compared to 48.2 % of non-trauma patients (p = 0.16). There were no significant differences between the two groups with regards to urine drug test results or acute care utilization in the follow-up period.

CONCLUSIONS

Among hospitalized patients with OUD who initiate buprenorphine, those who were hospitalized for trauma were at least as likely to link to out-patient treatment. Trauma admissions represent an important opportunity for diagnosing and linking patients with OUD to buprenorphine treatment.

摘要

背景

阿片类药物滥用危机仍在持续,导致大量患者出现发病和死亡。尽管阿片类药物使用障碍(OUD)的治疗方法有效,但只有少数患者接受这些治疗。创伤住院患者中 OUD 很常见,住院可能是开始使用药物并与持续的丁丙诺啡治疗相联系的机会。

方法

本回顾性队列研究基于电子病历审查,纳入符合以下条件的患者:(1)2018 年 1 月 1 日至 2019 年 6 月 30 日期间住院;(2)年龄≥18 岁;(3)接受过成瘾医学咨询服务;(4)开始使用丁丙诺啡,计划出院后继续使用。描述性统计分析了创伤组和非创伤组之间的差异,回归分析确定了 30 天丁丙诺啡随访的预测因素。

结果

在 197 名符合条件的患者中,60 名(30.5%)因创伤住院。与非创伤患者相比,创伤患者更年轻,更有可能就业,更有可能报告使用大麻和烟草,更少可能最近注射药物,住院时间更长。在有随访数据的患者中(n=147),63.2%的创伤患者在 30 天内就诊,而非创伤患者为 48.2%(p=0.16)。两组在随访期间的尿液药物检测结果或急性护理利用方面无显著差异。

结论

在开始使用丁丙诺啡的 OUD 住院患者中,因创伤住院的患者与门诊治疗的联系至少同样多。创伤入院是诊断和将 OUD 患者与丁丙诺啡治疗联系起来的重要机会。

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