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声门上成形术治疗重度喉软化症。我们能否预测成功?

Supraglottoplasty for severe laryngomalacia. Can we predict success?

机构信息

Otolaryngology Head and Neck Surgery Department, Shaare Zedek Medical Center, Affiliated to the Hebrew University, School of Medicine, Jerusalem, Israel.

Pediatric Pulmonary Institute, Shaare Zedek Medical Center, Affiliated to the Hebrew University, School of Medicine, Jerusalem, Israel.

出版信息

Int J Pediatr Otorhinolaryngol. 2020 Nov;138:110333. doi: 10.1016/j.ijporl.2020.110333. Epub 2020 Aug 28.

Abstract

OBJECTIVES

Laryngomalacia is the dynamic collapse of supraglottic structures during inspiration, leading to a variable degree of airway obstruction. Clinical symptoms appear in the first months of life and are usually mild and resolve by the age of 12-18 months. In severe cases, surgical intervention may be considered. The goal of the study was to review the clinical outcome of pediatric patients who underwent supraglottoplasty for laryngomalacia.

MATERIAL AND METHODS

Clinical and demographic data were retrieved from medical records of children diagnosed with laryngomalacia by laryngo-bronchoscopy between 2013 and 2019. Indications, outcome and long-term follow-up were collected from children undergoing surgery.

RESULTS

During the study period, 115 children were diagnosed with laryngomalacia. The median age at diagnosis was 3 months. Synchronous airway lesions were diagnosed in 20% of patients. Ten (8.7%) children underwent surgical treatment because of significant respiratory symptoms and/or failure to thrive. Three of them had comorbidities. All otherwise healthy children had significant respiratory and nutritional improvement after surgery while those with comorbidities had less successful outcomes.

CONCLUSION

We conclude that in severe cases of laryngomalacia, supraglottoplasty has an important role to play in management. In children with comorbidities, the surgical results may be less successful. Therefore, we recommend that the decision to operate should be individualized, ensuring full disclosure to the family regarding the probable benefit along with the limitations of surgery.

摘要

目的

喉软化症是指吸气时会厌和声门上方结构的动态塌陷,导致不同程度的气道阻塞。临床症状出现在生命的头几个月,通常较为轻微,并在 12-18 个月龄时缓解。在严重的情况下,可能需要考虑手术干预。本研究旨在回顾接受杓状软骨成形术治疗喉软化症的儿科患者的临床转归。

材料与方法

从 2013 年至 2019 年间通过喉支气管镜诊断为喉软化症的患儿的病历中提取临床和人口统计学数据。收集了接受手术治疗的患儿的适应证、转归和长期随访资料。

结果

在研究期间,共诊断出 115 例喉软化症患儿。中位诊断年龄为 3 个月。20%的患儿同时存在气道病变。由于存在明显的呼吸症状和/或生长发育不良,10 例(8.7%)患儿接受了手术治疗。其中 3 例患儿合并其他疾病。所有其他健康的患儿在手术后呼吸和营养状况均有显著改善,而合并其他疾病的患儿手术效果较差。

结论

我们认为,在严重的喉软化症病例中,杓状软骨成形术在治疗中具有重要作用。对于合并其他疾病的患儿,手术结果可能不太理想。因此,我们建议应根据患儿具体情况制定个体化的治疗方案,充分向患儿家属告知手术的预期获益及局限性。

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