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症状性脑动静脉畸形的显微外科治疗-单中心经验。

Microsurgical approach for symptomatic brain AVMs - single center experience.

机构信息

Department of Neurosurgery, University of Medicine and Pharmacy "Carol Davila" , Bucahrest, Romania.

Department of Neurosurgery, "Bagdasar-Arseni" Clinical Emergency Hospital , Bucharest, Romania.

出版信息

Neurol Res. 2020 Dec;42(12):1080-1084. doi: 10.1080/01616412.2020.1803604. Epub 2020 Sep 5.

Abstract

: Brain arteriovenous malformations (AVMs) represent high-flow vascular lesions made up of a complex network of feeding arteries and draining veins interposed by a nidus and without a capillary bed. The management of the AVMs represents a challenge, and the optimal treatment should be considered based on the particularities of each AVM. This paper aims to provide outcome data for the cohort of patients with AVMs that underwent surgical treatment. : A retrospective review of patients who presented with AVMs between 2001 and 2019 was conducted. Patients were included if they underwent surgery, preoperative and postoperative angiographic studies were available. : 91 patients were included. The SM grade was 1 in 16 cases (17,6%), 2 in 27 patients (29.7%), 3 in 29 patients (31,9%), 4 in 12 cases (13.2%) and grade 5 in 7 cases (7.7%). In 58 (63.7%) cases the AVMs were ruptured. Complete microsurgical resection was achieved in 82 cases (90.1%). Unruptured AVM (87.9% vs. 63.8% for ruptured AVMs; p = 0.015), low-grade AVM (86% vs. 60.4% for grade III-V AVMs; p = 0.006) and cortical location (79.5% vs. 30.8% for deep AVM; p < 0.0001) were the factors associated with a good outcome on mRS scale. : Microsurgical resection is the curative treatment for AVMs and offers a good functional outcome if selection criteria are met.

摘要

脑动静脉畸形(AVM)是由供血动脉和引流静脉组成的复杂网络构成的高流量血管病变,其间有一个核心,没有毛细血管床。AVM 的治疗是一个挑战,应该根据每个 AVM 的特点考虑最佳治疗方法。本文旨在提供接受手术治疗的 AVM 患者的结果数据。

回顾性分析了 2001 年至 2019 年间就诊的 AVM 患者。纳入标准为接受手术治疗,且术前和术后血管造影研究均可用。

共纳入 91 例患者。SM 分级为 1 级 16 例(17.6%),2 级 27 例(29.7%),3 级 29 例(31.9%),4 级 12 例(13.2%),5 级 7 例(7.7%)。58 例(63.7%)AVM 破裂。82 例(90.1%)患者达到完全显微镜下切除。未破裂的 AVM(87.9% vs. 破裂的 AVM 为 63.8%;p = 0.015)、低分级 AVM(86% vs. 分级为 III-V 的 AVM 为 60.4%;p = 0.006)和皮质位置(79.5% vs. 深部 AVM 为 30.8%;p < 0.0001)是 mRS 量表上良好预后的相关因素。

显微外科切除是 AVM 的治疗方法,如果符合选择标准,可获得良好的功能预后。

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