Department of Anesthesiology, Intensive Care and Pain Medicine, University of Münster, Albert-Schweitzer-Campus 1, Building A1, Münster 48149, Germany.
Department of Anesthesiology, Intensive Care and Pain Medicine, University of Münster, Albert-Schweitzer-Campus 1, Building A1, Münster 48149, Germany.
Crit Care Clin. 2020 Oct;36(4):691-704. doi: 10.1016/j.ccc.2020.07.002. Epub 2020 Aug 13.
Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common complication after cardiac surgery and associated with a worse outcome. The pathogenesis of CSA-AKI is complex and multifactorial. Therapeutic options for severe CSA-AKI are limited to renal replacement therapy constituting a supportive measure. Therefore, risk identification, prevention, and early diagnosis are of utmost importance to improve patient outcomes. This review aims to provide an overview of the diagnosis, pathophysiologic mechanisms, and risk factors of CSA-AKI and delineates the strategies for AKI prevention available to improve patient outcomes after cardiac surgery.
心脏手术后急性肾损伤（CSA-AKI）是心脏手术后常见的并发症，与更差的预后相关。CSA-AKI 的发病机制复杂且多因素。严重 CSA-AKI 的治疗选择仅限于构成支持措施的肾脏替代疗法。因此，风险识别、预防和早期诊断对于改善患者结局至关重要。本综述旨在提供 CSA-AKI 的诊断、病理生理机制和危险因素的概述，并描述可改善心脏手术后患者结局的 AKI 预防策略。
