通过酶免疫测定法测定人类包虫病中的总IgE和特异性IgE水平。I. 术前水平。

Total and specific IgE levels in human hydatid disease determined by enzyme-immunoassay. I. Preoperative levels.

作者信息

Abril M J, Guisantes J A

机构信息

Department of Microbiology and Parasitology, University of Navarra, Pamplona, Spain.

出版信息

Allergol Immunopathol (Madr). 1988 Jan-Feb;16(1):49-52.

PMID:3289333

Abstract

The levels of total IgE and specific IgE in preoperative sera from 29 adult patients with surgically confirmed hydatidosis were studied by means of enzyme-immunoassay. Sera from 88 healthy donors were likewise studied. Findings showed that in the majority of the hydatidosis cases there was an increase of specific IgE and total IgE although individual variance was significant. Determination of total IgE as the only serological diagnostic test is not valid, since 27.5% of patients showed a total IgE level within normal values. Moreover, the determination of specific IgE has more diagnostic value than that of total IgE although it must be taken into account that in 7% of human hydatidosis cases there are no detectable levels of anti-Echinococcus IgE.

摘要

采用酶免疫分析法对29例经手术确诊为包虫病的成年患者术前血清中的总IgE和特异性IgE水平进行了研究。同样对88名健康供者的血清进行了研究。结果显示，在大多数包虫病病例中，特异性IgE和总IgE均升高，尽管个体差异显著。仅将总IgE测定作为唯一的血清学诊断试验是无效的，因为27.5%的患者总IgE水平在正常范围内。此外，特异性IgE的测定比总IgE具有更高的诊断价值，不过必须考虑到，在7%的人类包虫病病例中检测不到抗棘球绦虫IgE水平。