School of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
School of Nursing, The Hong Kong Polytechnic University, Hong Kong, China.
Eur J Cancer Care (Engl). 2022 Sep;31(5):e13314. doi: 10.1111/ecc.13314. Epub 2020 Sep 7.
To evaluate the feasibility and potential effects of patient-centred self-administered acupressure for alleviating fatigue and co-occurring symptoms among Chinese advanced cancer patients receiving treatment.
Thirty advanced cancer patients who screened positive for moderate/severe fatigue with symptoms of insomnia and/or pain were recruited from a hospital in Hong Kong. They were randomly assigned (1:1) to receive a 4-week patient-centred self-administered acupressure intervention or health education. Fatigue (primary outcome) and secondary outcomes (sleep quality, pain, fatigue-sleep disturbance-pain symptom cluster severity, anxiety, depression and quality of life) were measured by questionnaires and actigraphy.
Twenty-four participants (80%) completed the study. Adherence to self-administered acupressure practice was satisfactory, with all retained participants attending all sessions and 90.9% practising acupressure daily. All completers rated the class as very enjoyable or quite enjoyable. Fatigue, pain, symptom cluster severity, anxiety, depression and quality of life appeared to improve from baseline to post-intervention in the intervention group. Among these outcomes, only the between-group difference in anxiety post-intervention was significant. The group × time interaction effect was nonsignificant for all outcomes.
Patient-centred self-administered acupressure appears to be feasible and acceptable among advanced cancer patients. A fully powered trial is warranted to confirm the intervention effect.
评估以患者为中心的自我实施穴位按压对缓解接受治疗的中国晚期癌症患者的疲劳和并发症状的可行性和潜在效果。
从香港的一家医院招募了 30 名筛选出有中度/重度疲劳且伴有失眠和/或疼痛症状的阳性晚期癌症患者。他们被随机分配（1:1）接受为期 4 周的以患者为中心的自我实施穴位按压干预或健康教育。通过问卷和活动记录仪测量疲劳（主要结果）和次要结果（睡眠质量、疼痛、疲劳-睡眠障碍-疼痛症状群严重程度、焦虑、抑郁和生活质量）。
24 名参与者（80%）完成了研究。自我实施穴位按压练习的依从性令人满意，所有保留参与者都参加了所有课程，90.9%的人每天都进行穴位按压练习。所有完成者都将该课程评为非常愉快或相当愉快。干预组的疲劳、疼痛、症状群严重程度、焦虑、抑郁和生活质量似乎从基线到干预后都有所改善。在这些结果中，只有干预后焦虑的组间差异具有统计学意义。对于所有结果，组间×时间交互效应均无统计学意义。
以患者为中心的自我实施穴位按压在晚期癌症患者中似乎是可行且可接受的。需要进行一项充分的试验来确认干预效果。
