Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.
Department of Radiology, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Clin Radiol. 2020 Nov;75(11):864-867. doi: 10.1016/j.crad.2020.08.009. Epub 2020 Sep 28.
To describe patterns and risk factors of multiple recurrences to optimise management for pediatric patients with more than four episodes of intussusception.
Following IRB approval, all sonographic evaluations for intussusception in patients <18 years over a 6-year period were reviewed. Data extracted included age at onset of first intussusception, gender, presenting symptoms, symptoms upon recurrence, presence of pathological lead points, and surgical findings.
During a 6-year period, five cases had four or more instances of recurrence after enema reduction attempts. All patients were male with an average age of 16 months. Two of the five cases resolved after the fourth enema reduction and no lead points were identified. Two other cases involved surgical reduction with intraoperative findings of Meckel's diverticulum and juvenile polyp. The final case had five recurrence episodes and six separate enema reductions. Ultimately, lymphoid hyperplasia was discovered on colonoscopy and the patient never recurred after being treated with steroids.
Given the favorable reduction rate in re-recurrent cases and complete lack of perforation observed, up to four attempts at enema reduction is recommended before considering an alternative strategy. If recurrence continues past the fourth reduction attempt, computed tomography (CT) is recommended to identify a lead point. If CT remains inconclusive, then consider exploratory laparotomy.
描述多次复发的模式和风险因素,以优化儿科患者(肠套叠发作超过 4 次)的管理。
在获得机构审查委员会批准后,对 6 年来接受肠套叠超声检查的<18 岁患者进行了回顾性研究。提取的数据包括首次肠套叠发作的年龄、性别、首发症状、复发时的症状、病理性肠套叠的位置和手术发现。
在 6 年期间,5 例患者在尝试肠套叠灌肠复位后发生了 4 次或以上的复发。所有患者均为男性,平均年龄为 16 个月。其中 2 例在第四次灌肠复位后自行缓解,未发现肠套叠位置。另外 2 例需要手术复位,术中发现梅克尔憩室和幼年性息肉。最后 1 例患者发生了 5 次肠套叠复发和 6 次肠套叠灌肠复位。最终,结肠镜检查发现了淋巴组织增生,患者在接受类固醇治疗后从未再复发。
鉴于再次肠套叠的复位率较高,且观察到无穿孔发生,建议在考虑替代治疗方案之前,最多尝试 4 次肠套叠灌肠复位。如果第四次肠套叠复位后仍持续复发,建议行 CT 以明确肠套叠位置。如果 CT 仍不明确,则考虑剖腹探查。