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入院时的高血糖与预后不良密切相关,早期干预可以改善 COVID-19 患者的结局。

At-admission hyperglycemia is consistently associated with poor prognosis and early intervention can improve outcomes in patients with COVID-19.

机构信息

Department of Diabetes & Endocrinology, G.D Hospital & Diabetes Institute, Kolkata, India.

出版信息

Diabetes Metab Syndr. 2020 Nov-Dec;14(6):1641-1644. doi: 10.1016/j.dsx.2020.08.034. Epub 2020 Aug 29.

Abstract

BACKGROUND & AIMS: At-admission hyperglycemia have been associated with poorer outcome during critical illnesses. At-admission hyperglycemia in previously unknown diabetes is not uncommonly encountered entity in patients with COVID-19. We sought to find out the outcomes of at-admission hyperglycemia and effect of early intervention to achieve optimal glycemic control in relation to COVID-19 patients.

METHODS

We searched the PubMed and Google Scholar database up till August 20, 2020 using specific keywords related to our aims and objectives.

RESULTS

All currently available evidences clearly hint that at-admission hyperglycemia in patients with COVID-19 is associated with a poorer outcome, compared with normoglycemic individuals. Fortunately, early intervention by achieving an optimal glycemic control has also been associated with a significant improvement in the outcomes in patients with COVID-19.

CONCLUSION

At-admission hyperglycemia should be taken seriously by all clinicians treating patients with COVID-19. All efforts should be made towards an optimal glycemic control in patients with COVID-19, even in absence of pre-existing diabetes.

摘要

背景与目的

入院时的高血糖与危重疾病期间的不良预后相关。在 COVID-19 患者中,以前未确诊的糖尿病患者中常见入院时高血糖。我们试图了解入院时高血糖的结果,以及早期干预以实现最佳血糖控制对 COVID-19 患者的影响。

方法

我们使用与目标相关的特定关键字,在 2020 年 8 月 20 日之前搜索了 PubMed 和 Google Scholar 数据库。

结果

所有现有证据清楚地表明,与血糖正常的个体相比,COVID-19 患者的入院时高血糖与较差的预后相关。幸运的是,通过实现最佳血糖控制进行早期干预也与 COVID-19 患者的结局显著改善相关。

结论

治疗 COVID-19 患者的所有临床医生都应认真对待入院时的高血糖。应尽一切努力使 COVID-19 患者的血糖控制达到最佳,即使在没有预先存在的糖尿病的情况下也是如此。

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