Turner Institute for Brain and Mental Health, and School of Psychological Sciences, Monash University, Clayton, Victoria, Australia (Drs Spiteri, Ponsford, and McKay); Epworth Healthcare, Richmond, Victoria, Australia (Drs Spiteri, Ponsford, and McKay); and Epworth Healthcare, Victoria, Australia (Drs Jones and McKay).
J Head Trauma Rehabil. 2021;36(3):156-163. doi: 10.1097/HTR.0000000000000607.
The duration of the acute period of recovery following traumatic brain injury (TBI) remains a widely used criterion for injury severity and clinical management. Consensus regarding its most appropriate definition and assessment method has yet to be established.
The present study compared the trajectory of recovery using 3 measures: the Westmead Post-Traumatic Amnesia Scale (WPTAS), the Galveston Orientation and Amnesia Test (GOAT), and the Confusion Assessment Protocol (CAP). Patterns of symptom recovery using the CAP were explored.
Eighty-two participants with moderate to severe TBI in posttraumatic amnesia (PTA) on admission to an inpatient rehabilitation hospital.
Prospective longitudinal study.
Length of PTA (days), agreement between measures (%, κ coefficient), and pattern of symptom recovery.
Participants emerged from PTA earliest on the CAP followed the GOAT, and last on the WPTAS. There was good agreement between the CAP and the GOAT as to PTA status, but both tests had poor agreement with the WPTAS. Of patients considered out of PTA on the CAP, the majority exhibited signs of amnesia on the WPTAS and one-third had clinical levels of agitation.
The WPTAS identifies a later stage of PTA recovery that requires specialized management due to ongoing amnesia and agitation. The CAP and the GOAT are less sensitive to this extended period of PTA.
创伤性脑损伤 (TBI) 后急性恢复期的持续时间仍然是广泛用于衡量损伤严重程度和临床管理的标准。但目前尚未就其最合适的定义和评估方法达成共识。
本研究比较了使用三种方法(西梅德创伤后遗忘量表 (WPTAS)、加尔维斯顿定向和遗忘测试 (GOAT) 和意识模糊评估量表 (CAP))来评估恢复轨迹。还探索了使用 CAP 评估症状恢复的模式。
82 名在创伤后遗忘期 (PTA) 进入住院康复医院的中度至重度 TBI 患者。
前瞻性纵向研究。
PTA 持续时间(天)、各测量指标之间的一致性(%,κ 系数)和症状恢复模式。
患者最早从 CAP 中脱离 PTA,其次是 GOAT,最后是 WPTAS。CAP 和 GOAT 对 PTA 状态的判断具有良好的一致性,但与 WPTAS 的一致性均较差。在被认为脱离 CAP 中的 PTA 的患者中,大多数在 WPTAS 上仍存在记忆障碍,三分之一的患者出现临床激越。
WPTAS 识别出 PTA 恢复期的一个较晚阶段,由于持续存在的遗忘和激越,需要特殊管理。CAP 和 GOAT 对这一延长的 PTA 阶段的敏感性较低。