J. Verspeek, T. Nijenhuis, M. F. L. Kuijpers, W. H. C. Rijnen, B. W. Schreurs, Radboud University Medical Center, Radboud Institute for Health Sciences, Department of Orthopaedics, Nijmegen, The Netherlands.
Clin Orthop Relat Res. 2021 Jan 1;479(1):84-91. doi: 10.1097/CORR.0000000000001462.
The increasing number of THAs in younger patients will inevitably result in an increase of revision procedures. However, there is little evidence about the outcome of revision procedures in this patient group. Therefore, we updated a previous study conducted 5 years ago about the outcome of revision procedures in patients younger than 55 years.
QUESTIONS/PURPOSES: We sought to provide a concise update on the previously reported (1) long-term failure rate as defined by repeat revision, (2) clinical outcome as defined by the Oxford Hip score and the Harris Hip score, and (3) radiographic outcome of cemented revision THA performed with impaction bone grafting on both the acetabular and femoral sides in one surgery in patients younger than 55 years old.
Between 1991 and 2007, we performed 86 complete THA revisions in patients younger than 55 years. In 38% (33 of 86) of revisions, bone impaction grafting was used on both the acetabular and femoral side because of acetabular and femoral bone stock loss. Mean age at time of revision was 46 ± 8 years. No patient was lost to follow-up, but six patients died during follow-up, including three since 2015. Still, the hips of all 33 patients were included in analysis at a mean of 17 ± 5 years. Failure was calculated using competing risk analysis. For clinical outcome, we assessed the Harris Hip score and the Oxford Hip score from our longitudinally maintained institutional database. Radiographic analysis was performed to evaluate radiographic loosening, defined as radiolucencies ≥ 2 mm in all zones or ≥ 5 mm migration for both components. The acetabular component was also considered loose with tilting ≥ 5°.
The 15-year failure rate of revision THA was 27% (95% CI 13 to 44) for re-revision of any component for any reason and 10% (95% CI 3 to 25) for re-revision of any component for aseptic loosening. The mean Harris Hip score increased from 55 ± 18 preoperatively to 74 ± 22 at latest follow-up. Eight cups were considered radiographically loose, seven of which were re-revised. No stems were considered radiographically loose. Failure rate with endpoint radiographic loosening at 15 years was 23% (95% CI 10 to 39).
We found that impaction bone grafting with a cemented cup and a cemented stem is a valuable biological revision technique that results in a stable and durable solution, after one or even multiple previous revision THAs. Although current implants may prove sufficient in most cases, they do not promote bone stock preservation. We believe that in young patients with bone stock loss, impaction bone grafting can be used as long as the defect can be contained adequately with a metal mesh and viable bone bed is available for revascularization.
Level IV, therapeutic study.
越来越多的年轻患者接受髋关节置换术,这不可避免地导致翻修手术数量的增加。然而,关于这一年龄组患者翻修手术结果的证据有限。因此,我们更新了 5 年前进行的一项关于 55 岁以下患者翻修手术结果的研究。
问题/目的:我们旨在提供一份简明的更新报告,内容包括:(1)以前报道的翻修手术的长期失败率(定义为再次翻修);(2)临床结果,定义为牛津髋关节评分和 Harris 髋关节评分;(3)在同一手术中使用骨水泥髋臼和股骨侧打压植骨的翻修全髋关节置换术的影像学结果。
1991 年至 2007 年间,我们对 86 例 55 岁以下的患者进行了全髋关节翻修手术。在 38%(33/86)的翻修手术中,由于髋臼和股骨骨量丢失,使用了髋臼和股骨侧打压植骨。翻修时的平均年龄为 46±8 岁。无患者失访,但在随访期间有 6 例患者死亡,其中 3 例发生在 2015 年之后。尽管如此,在平均 17±5 年的随访中,仍有 33 例患者的所有髋关节均纳入分析。采用竞争风险分析计算失败率。对于临床结果,我们从我们纵向维护的机构数据库中评估了 Harris 髋关节评分和牛津髋关节评分。进行影像学分析以评估影像学松动,定义为所有区域的透亮线≥2mm 或任何组件的迁移≥5mm。髋臼组件也被认为是松动的,倾斜度≥5°。
任何原因的任何组件再次翻修的 15 年失败率为 27%(95%CI,13%至 44%),因无菌性松动而再次翻修的任何组件的失败率为 10%(95%CI,3%至 25%)。术前 Harris 髋关节评分为 55±18,术后随访时平均为 74±22。8 个髋臼杯被认为存在影像学松动,其中 7 个进行了再次翻修。没有股骨柄被认为存在影像学松动。15 年时影像学松动的失败率为 23%(95%CI,10%至 39%)。
我们发现,使用骨水泥髋臼和骨水泥股骨柄进行打压植骨是一种有价值的生物学翻修技术,可为 1 次或多次翻修后的全髋关节置换术提供稳定和持久的解决方案。尽管目前的植入物在大多数情况下可能已经足够,但它们并不能促进骨量的保存。我们认为,在有骨量丢失的年轻患者中,只要可以用金属网充分覆盖缺损,并且有可用的有血管化的骨床,就可以使用打压植骨。
IV 级,治疗性研究。