Rossi P, Pavone P, Castrucci M, Piscitelli G
Second Chair of Radiology, La Sapienza University, Rome, Italy.
Eur J Radiol. 1988 May;8(2):85-8.
The results of a comparative double-blind clinical trial involving peripheral intra-arterial DSA performed with low iodine iopamidol concentrations (150 and 200 mg. I/ml.) are reported. Forty-six patients were examined for vital signs, local (heat and pain sensations) and systemic reactions and monitored throughout the procedure. No untoward effect was observed apart from mild local reactions, which on the other hand did not produce any movement artifacts. Image quality was good to optimal in 98% of the cases. In no case were higher concentrations of contrast medium (cm) needed. No significant differences between the two concentrations of cm used were observed with respect to either contrast ability or tolerability.
报告了一项比较双盲临床试验的结果,该试验涉及使用低碘浓度(150和200mg.I/ml)的碘帕醇进行外周动脉内数字减影血管造影(DSA)。对46名患者进行了生命体征、局部(热感和痛感)及全身反应检查,并在整个过程中进行监测。除了轻微的局部反应外,未观察到不良影响,而这些局部反应另一方面并未产生任何运动伪影。98%的病例图像质量良好至最佳。在任何情况下都不需要更高浓度的造影剂(CM)。在所使用的两种CM浓度之间,在造影能力或耐受性方面均未观察到显著差异。