Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, PO Box 8030, Yale Station, New Haven, CT, 06520, USA.
VACS Coordination Center, Veterans Administration Connecticut Healthcare System, 950 Campbell Avenue, West Haven, CT, 06516, USA.
AIDS Behav. 2021 Mar;25(3):653-660. doi: 10.1007/s10461-020-03028-4.
Religion and spirituality have been associated with higher survival and improved biological markers among people living with HIV/AIDS (PLWH). Prior results have largely been among small cohort studies. We examined the association using a larger sample and longitudinal data from the Veterans Aging Cohort Study (VACS) years 2002-2012 (n = 3,685). Attending services at least monthly was associated with higher social support (80% vs 75%, p = 0.002), less unhealthy alcohol use (35% vs 39%, p = 0.006), less marijuana use in the past year (23% vs 32%, p < 0.001), less overall drug use within the past year (27% vs 31%, p = 0.01), and lower depression (20% vs 24%, p = 0.004). Attending services monthly was associated with a reduced mortality risk adjusting for age, race, gender, education, MSM, HCV, VL, CD4, and adherence to ARV (adjusted HazardRatio [aHR] = 0.89, 0.80-0.99). However, after controlling for smoking status, this association of mortality and religious attendance became non-significant (aHR = 0.93, 0.84-1.04).
宗教和精神信仰与艾滋病毒/艾滋病感染者（PLWH）的更高存活率和改善的生物学标志物有关。先前的研究结果主要来自小队列研究。我们使用更大的样本和退伍军人老龄化队列研究（VACS）2002-2012 年的纵向数据（n=3685）来检验这种关联。每月至少参加一次宗教活动与更高的社会支持（80%比 75%，p=0.002）、更少的不健康饮酒（35%比 39%，p=0.006）、过去一年更少的大麻使用（23%比 32%，p<0.001）、过去一年中更少的总体药物使用（27%比 31%，p=0.01）和更低的抑郁发生率（20%比 24%，p=0.004）有关。调整年龄、种族、性别、教育程度、男男性行为、丙型肝炎、病毒载量、CD4 计数和抗逆转录病毒药物依从性后，每月参加宗教活动与降低死亡率相关（调整后的危险比[aHR]=0.89，0.80-0.99）。然而，在控制吸烟状况后，这种与死亡率和宗教参与的关联变得不显著（aHR=0.93，0.84-1.04）。
