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一项关于T3与T4胸腔镜交感神经切除术治疗原发性手掌多汗症以及伴有腋窝和足底出汗的原发性手掌多汗症的回顾性队列研究。

A retrospective cohort study of T3 versus T4 thoracoscopic sympathectomy for primary palmar hyperhidrosis and primary palmar hyperhidrosis with axillary and plantar sweating.

作者信息

Xie Hongya, Lu Tao, Zhu Yimeng, Zhu Donglin, Wei Tengteng, Yuan Guangda, Yang Yong, Liu Xiaoqiang

机构信息

Department of Thoracic Surgery, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou City, Jiangsu Province, China.

Department of Thoracic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.

出版信息

Wideochir Inne Tech Maloinwazyjne. 2020 Sep;15(3):488-495. doi: 10.5114/wiitm.2019.89656. Epub 2019 Nov 11.

Abstract

INTRODUCTION

Thoracoscopic sympathectomy (TS) has been proven to be a safe and effective treatment for primary palmar hyperhidrosis (PH). However, the complications include compensatory hyperhidrosis (CH), and over-dry hands may occur in some patients after TS.

AIM

To compare the therapeutic effect of T3 and T4 TS on primary PH and primary PH with axillary and plantar sweating.

MATERIAL AND METHODS

We retrospectively analyzed 100 patients with PH who had undergone T3 (group A, n = 49) or T4 (group B, n = 51) TS in our department, with at least 1 year of postoperative follow-up.

RESULTS

At discharge, no major complications or deaths occurred in either group. The condition of sweaty hands was fully improved in 44 of 49 patients in group A and all patients in group B, with a significant difference (p = 0.031). After 12 months of follow-up, 18 (36.7%) patients in group A and 4 (7.8%) patients in group B developed CH, 16 (48.5%) patients in group A and 24 (77.4%) patients in group B had improved axillary sweating, with a significant difference (p < 0.05). The satisfaction rate of group B was significantly higher than that of group A (p < 0.01).

CONCLUSIONS

Both T3 and T4 TS were safe and effective treatments for PH patients, but the incidence of CH in T4 TS was lower than that in T3 TS. T3 TS may be more suitable for patients with severe PH, while T4 TS had a better therapeutic effect on PH patients with axillary sweating.

摘要

引言

胸腔镜交感神经切除术(TS)已被证明是治疗原发性手掌多汗症(PH)的一种安全有效的方法。然而,其并发症包括代偿性多汗(CH),并且一些患者在TS术后可能会出现手部过度干燥。

目的

比较T3和T4胸腔镜交感神经切除术治疗原发性手掌多汗症以及原发性手掌多汗症合并腋窝和足底多汗症的疗效。

材料与方法

我们回顾性分析了在我科接受T3(A组,n = 49)或T4(B组,n = 51)胸腔镜交感神经切除术的100例多汗症患者,术后随访至少1年。

结果

出院时,两组均未发生重大并发症或死亡。A组49例患者中的44例和B组所有患者的手部多汗情况均得到完全改善,差异有统计学意义(p = 0.031)。随访12个月后,A组18例(36.7%)患者和B组4例(7.8%)患者出现代偿性多汗,A组16例(48.5%)患者和B组24例(77.4%)患者的腋窝多汗情况有所改善,差异有统计学意义(p < 0.05)。B组的满意度显著高于A组(p < 0.01)。

结论

T3和T4胸腔镜交感神经切除术对多汗症患者均是安全有效的治疗方法,但T4胸腔镜交感神经切除术的代偿性多汗发生率低于T3胸腔镜交感神经切除术。T3胸腔镜交感神经切除术可能更适合重度多汗症患者,而T4胸腔镜交感神经切除术对合并腋窝多汗的多汗症患者具有更好的治疗效果。

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A systematic review of microwave-based therapy for axillary hyperhidrosis.基于微波治疗腋窝多汗症的系统评价。
J Cosmet Laser Ther. 2017 Oct;19(5):275-282. doi: 10.1080/14764172.2017.1303168. Epub 2017 Mar 10.
2
Thoracoscopic sympathicotomy in the treatment of palmar hyperhidrosis.胸腔镜交感神经切断术治疗手掌多汗症。
Asian Cardiovasc Thorac Ann. 2016 Sep;24(7):687-91. doi: 10.1177/0218492316657729. Epub 2016 Jun 28.

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