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静脉血栓栓塞预防方案:全膝关节置换术2000例经验

Venous Thromboembolism Prevention Protocol: Experience of 2,000 Cases in Total Knee Arthroplasty.

作者信息

Carvalho Júnior Lúcio Honório de, Correa Matheus de Almeida, Lima Matheus Rezende, Silvestre Camila Barreto, Almeida Victor Ferreira, Temponi Eduardo Frois

机构信息

Grupo de Joelho, Serviço de Ortopedia e Traumatologia, Hospital Madre Teresa, Belo Horizonte, MG, Brasil.

Departamento de Medicina, Pontifícia Universidade Católica, Belo Horizonte, MG, Brasil.

出版信息

Rev Bras Ortop (Sao Paulo). 2020 Aug;55(4):426-431. doi: 10.1055/s-0039-1698798. Epub 2019 Dec 13.

Abstract

The objective of the present study is to evaluate the impact evaluate the impact of an institutional protocol on a tertiary hospital for the prevention of venous thromboembolism in 2005 patients submitted to primary total knee arthroplasty (TKA).  Data from medical records of patients submitted TKA before (  = 1,115) and after (  = 890) the implementation of the institutional protocol, totaling 2,005 patients, were retrospectively reported. Demographics, comorbidities, and outcomes were analyzed.  There was no significant change in the cases of deep venous thrombosis (DVT) (1.6% versus 2.4%;  = 0.211). There was an increase in cases of pulmonary embolism (PE) (0.2% versus 0.8%  = 0.049).  Despite the implementation of the prevention protocol, no reduction in the studied events was observed. The small global incidence makes further studies with larger series necessary to confirm or rule out these findings.

摘要

本研究的目的是评估一项机构方案对一家三级医院2005例接受初次全膝关节置换术(TKA)患者预防静脉血栓栓塞的影响。回顾性报告了实施该机构方案前后接受TKA患者的病历数据,其中实施前(n = 1115),实施后(n = 890),共2005例患者。分析了人口统计学、合并症和结局。深静脉血栓形成(DVT)病例无显著变化(1.6%对2.4%;P = 0.211)。肺栓塞(PE)病例有所增加(0.2%对0.8%,P = 0.049)。尽管实施了预防方案,但未观察到所研究事件的减少。总体发生率较低,需要进一步开展更大样本量的研究来证实或排除这些发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1658/7458736/16fb1e09b52b/10-1055-s-0039-1698798-i1900030en-1.jpg

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