Rutgers Robert Wood Johnson Medical School, Department of Orthopaedic Surgery, New Brunswick, New Jersey.
University Orthopaedic Associates, New Brunswick, New Jersey.
J Arthroplasty. 2017 Dec;32(12):3735-3741. doi: 10.1016/j.arth.2017.06.042. Epub 2017 Jul 5.
Venous thromboembolism (VTE), including pulmonary embolism (PE) and deep vein thrombosis, is a serious complication after total joint arthroplasty (TJA). Risk assessment models are increasingly used to provide patient-specific risk stratification. A recently implemented protocol mandates calculation of a Caprini Score for all surgical patients at our institution. We investigated the accuracy of the Caprini Score in predicting VTE events following TJA.
A retrospective review of patients undergoing primary total hip (THA) and total knee arthroplasty (TKA) over a 1-year time period was performed. The 90-day postoperative incidence of emergency department evaluations, hospital readmissions, medical complications, need for revision surgery, and symptomatic VTE was recorded. "Preoperative" Caprini Scores routinely recorded per protocol and calculated during review ("Calculated") were compared and assessed for relationship with VTE events. A "VTEstimator" Score was calculated for each patient.
Three hundred seventy-six arthroplasties (151 TKA and 225 THA) meeting inclusion criteria were identified. Ten patients (2.5%) had symptomatic VTE postoperatively, with 3 pulmonary embolism (0.8%) and 7 deep vein thrombosis (1.8%). Eight VTE (5.3%) occurred following TKA and 2 (0.9%) occurred following THA. For each surgical characteristic evaluated, no significant difference was observed between mean Preoperative or Calculated Caprini Scores for patients with and without VTE (P > .05). Additionally, the distribution of VTEstimator Scores for patients with and without VTE was not significantly different (P = .93).
The Caprini risk assessment model does not appear to provide clinically useful risk stratification for TJA patients. Alternative risk stratification protocols may provide assistance in balancing safety and efficacy of thromboprophylaxis.
静脉血栓栓塞症(VTE),包括肺栓塞(PE)和深静脉血栓形成,是全关节置换术后(TJA)的严重并发症。风险评估模型越来越多地用于为患者提供特定的风险分层。我们机构最近实施的一项方案要求对所有手术患者计算卡普里尼评分。我们研究了卡普里尼评分在预测 TJA 后 VTE 事件中的准确性。
对一年内接受初次全髋关节置换术(THA)和全膝关节置换术(TKA)的患者进行回顾性研究。记录术后 90 天急诊评估、医院再入院、医疗并发症、需要翻修手术和有症状 VTE 的发生率。根据方案常规记录的“术前”卡普里尼评分(“常规记录”)和审查期间计算的评分(“计算”)进行比较,并评估与 VTE 事件的关系。为每位患者计算了“VTEstimator”评分。
确定了符合纳入标准的 376 例关节置换术(151 例 TKA 和 225 例 THA)。术后有 10 例(2.5%)患者出现有症状的 VTE,其中 3 例为肺栓塞(0.8%),7 例为深静脉血栓形成(1.8%)。8 例 VTE(5.3%)发生在 TKA 后,2 例(0.9%)发生在 THA 后。对于评估的每个手术特征,有 VTE 和无 VTE 的患者之间的常规记录或计算的卡普里尼评分的平均值没有显著差异(P>.05)。此外,有和无 VTE 的患者之间的 VTEstimator 评分分布也没有显著差异(P=0.93)。
卡普里尼风险评估模型似乎不能为 TJA 患者提供临床有用的风险分层。替代风险分层方案可能有助于平衡血栓预防的安全性和有效性。