1st Medical Clinic, Gastroenterology Department, Emergency Clinical County Hospital Cluj; Department of Internal Medicine, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Romania.
"Prof. Dr. Ioan Chiricuta" Oncology Institute Cluj-Napoca, Romania.
Med Ultrason. 2021 Aug 11;23(3):361-363. doi: 10.11152/mu-2499. Epub 2020 May 28.
Thoracic lymphangiomatosis (proliferation of anastomosing lymphatic vessels, of different sizes, in pulmonary, pleural and mediastinal regions) is an extremely rare disorder occurring mostly in childhood. We present a diffuse pulmonary lymphangiomatosis (DPL) case in a young adult female patient in which repeated surgical biopsies were inconclusive and transthoracic ultrasound-guided (TUS) biopsy led to the diagnosis. Even histologically, DPL is very difficult to differentiate from other lymphatic diseases such as lymphangioma and lymphangiomyomatosis, requiring an experienced pathologist and proper immunohistochemistry staining. This case highlights the importance of TUS-guided biopsies in the armamentarium of imagistic techniques in this very rare case.
胸导管淋巴组织增生症（不同大小的吻合淋巴管在肺、胸膜和纵隔区域的增生）是一种极其罕见的疾病，主要发生在儿童时期。我们报告了一例年轻成年女性弥漫性肺淋巴管瘤病（DPL）病例，反复的外科活检结果不确定，经胸超声引导（TUS）活检后确诊。即使在组织学上，DPL 也很难与其他淋巴疾病（如淋巴管瘤和淋巴管平滑肌瘤病）区分，这需要有经验的病理学家和适当的免疫组织化学染色。本病例强调了 TUS 引导活检在这种非常罕见病例的影像学技术中的重要性。
