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脊髓灰质炎——旧敌与新挑战:临床医生最新资讯

Polio - The old foe and new challenges: An update for clinicians.

作者信息

Bao Junchao, Thorley Bruce, Isaacs David, Dinsmore Nicole, Elliott Elizabeth J, McIntyre Peter, Britton Philip N

机构信息

Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.

Department of General Medicine, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.

出版信息

J Paediatr Child Health. 2020 Oct;56(10):1527-1532. doi: 10.1111/jpc.15140. Epub 2020 Sep 9.

DOI:10.1111/jpc.15140
PMID:32905647
Abstract

The Global Polio Eradication Initiative since 1988 has seen the impact of poliovirus decline from frequent global epidemics in the early 1900s to being now only endemic in two countries today. Global vaccination programmes and surveillance for the disease have resulted in the landmark eradication of two of the three poliovirus strains in the last 5 years. Australia continues to contribute to global surveillance efforts for the disease via the Australian Paediatric Surveillance Unit and the Paediatric Active Enhanced Disease Surveillance Network, which aim to detect cases of acute flaccid paralysis in children, the key clinical feature of poliomyelitis. Today, in the era of the polio 'endgame', there is growing recognition of non-polio enteroviruses causing paralytic diseases that are polio-like, particularly in children, with an increased need for awareness and vigilance by paediatric clinicians.

摘要

自1988年以来的全球根除脊髓灰质炎行动见证了脊髓灰质炎病毒的影响从20世纪初频繁的全球流行下降到如今仅在两个国家呈地方性流行。全球疫苗接种计划和该疾病监测已在过去5年中实现了三种脊髓灰质炎病毒株中的两种被里程碑式地根除。澳大利亚通过澳大利亚儿科监测单位和儿科主动强化疾病监测网络继续为该疾病的全球监测工作做出贡献,其目的是检测儿童急性弛缓性麻痹病例,这是脊髓灰质炎的关键临床特征。如今,在脊髓灰质炎“收官之战”的时代,人们越来越认识到非脊髓灰质炎肠道病毒会引发类似脊髓灰质炎的麻痹性疾病,尤其是在儿童中,儿科临床医生对其的认识和警惕需求也日益增加。

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