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急性脑卒中患者血管内治疗的频率和时机:基于布雷梅急性脑卒中登记的人群分析。

Frequency and Timing of Endovascular Therapy in Acute Stroke Patients: A Population-Based Analysis Using the Bremen Stroke Register.

机构信息

Department of Neurology, Klinikum Bremen-Mitte, Bremen, Germany,

Department of Neurology, Klinikum Bremen-Mitte, Bremen, Germany.

出版信息

Neuroepidemiology. 2020;54(5):398-403. doi: 10.1159/000509430. Epub 2020 Sep 9.

Abstract

BACKGROUND AND PURPOSE

In patients with large vessel occlusions (LVOs), endovascular treatment (ET) has become the standard of care, so that the potential number of these patients needs to be considered for the effective implementation of comprehensive stroke services. However, population-based data on the incidence of ET are scarce.

METHODS

Using our prospective stroke register, in which all endovascular procedures on the 557,464 inhabitants of the city of Bremen are included, we performed a population-based analysis on the frequency and timing of ET in acute stroke patients with LVOs in the year 2017.

RESULTS

Out of a total of 1,448 acute ischemic stroke patients, 173 patients (12%) had received ET (161 patients in the anterior circulation and 12 patients in the posterior circulation). Among these, 95 patients were inhabitants of Bremen. The population-based incidence thus was 17 (95% confidence interval [CI]: 14-21) ET cases per 100,000 person-years. The number of stroke procedures per month varied from 9 to 19 (median: 14.5; interquartile range [IQR]: 12-17). The number of stroke procedures per month and 100,000 inhabitants varied from 0.7 to 2.1 (median: 1.4; IQR: 0.9-1.7). Many procedures (53%) were performed during nonwork hours (between 17:00 h and 06:59 h or weekends).

CONCLUSIONS

Approximately 12% of all ischemic stroke patients received ET, and the incidence of ET was 17 (95% CI: 14-21) cases per 100,000 person-years. However, despite being a high-volume center, the absolute number of stroke procedures per month was low, and many patients were treated during nonwork hours.

摘要

背景与目的

在大血管闭塞(LVOs)患者中,血管内治疗(ET)已成为标准治疗方法,因此需要考虑这些患者的潜在数量,以有效实施全面的卒中服务。然而,基于人群的 ET 发病率数据很少。

方法

我们使用前瞻性卒中登记处,该登记处包括了不来梅市 557464 名居民的所有血管内治疗操作,对 2017 年急性 LVO 卒中患者 ET 的频率和时间进行了基于人群的分析。

结果

在总共 1448 例急性缺血性卒中患者中,有 173 例(12%)接受了 ET(前循环 161 例,后循环 12 例)。其中 95 例是不来梅居民。因此,基于人群的发病率为每 100000 人年 17(95%置信区间[CI]:14-21)例 ET 病例。每月的卒中手术数量从 9 到 19 例不等(中位数:14.5;四分位距[IQR]:12-17)。每月的卒中手术数量和每 100000 居民数量从 0.7 到 2.1 例不等(中位数:1.4;IQR:0.9-1.7)。许多手术(53%)在非工作时间(17:00 h 至 06:59 h 或周末)进行。

结论

大约 12%的缺血性卒中患者接受了 ET,ET 的发病率为每 100000 人年 17(95%CI:14-21)例。然而,尽管作为一个高容量中心,每月的卒中手术数量仍然较低,并且许多患者在非工作时间接受治疗。

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