无性螺旋鞭毛虫：系统发育分析及作为DNA探针检测结果假阳性原因的评估
Spiromastigoides asexualis: Phylogenetic Analysis and Evaluation as a Cause of False-Positive DNA Probe Test Results.
作者信息
Nguyen Minh-Vu H, Wiederhold Nathan P, Cañete-Gibas Connie, Sanders Carmita, Thompson George R
机构信息
Department of Internal Medicine, Division of Infectious Diseases, University of California-Davis Health, Davis, CA, USA.
Fungus Testing Laboratory, Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
出版信息
J Clin Microbiol. 2020 Nov 18;58(12). doi: 10.1128/JCM.01325-20.
Abstract
This is the first case of human infection, and it notably gave a false-positive DNA probe laboratory result. We further investigated other isolates as a cause of false-positive testing results, their phylogenetic relationship, and their susceptibility profiles to clinically available antifungal agents. Other isolates also resulted in positive DNA probe results, while species other than did not.
摘要
这是首例人类感染病例，值得注意的是，它在DNA探针实验室检测中给出了假阳性结果。我们进一步调查了其他分离株作为假阳性检测结果的原因、它们的系统发育关系以及它们对临床可用抗真菌药物的敏感性概况。其他分离株也导致了DNA探针检测结果呈阳性，而除[未提及的物种]之外的其他物种则没有。
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