卡拉巴尔献血者恒河猴血型的人口统计学：以尼日利亚克罗斯河州卡拉巴尔大学教学医院为例
Demographics of Rhesus Phenotype of Blood Donors in Calabar: A Case Study of University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria.
作者信息
Etura Joyce Ezekiel, Amaechi Rose A, Akpotuzor Josephine O, Okoroiwu Henshaw Uchechi
机构信息
Haematology Unit, Department of Medical Laboratory Science, University of Calabar, Calabar, Nigeria.
Haematology Unit, Department of Medical Laboratory Science, Ambrose Alli University, Ekpoma, Edo State, Nigeria.
出版信息
Adv Hematol. 2020 Aug 27;2020:2659398. doi: 10.1155/2020/2659398. eCollection 2020.
BACKGROUND
Rhesus antigens have been documented to cause haemolytic disease of the newborn as well as acute and delayed transfusion reactions. This study was performed to evaluate the frequency of rhesus antigens (C, c, D, E, and e) in the studied population.
METHOD
This study was a cross-sectional study involving 130 prospective blood donors attending University of Calabar Teaching Hospital (UCTH) donor clinic. Donors were grouped for Rh antisera (anti-E, anti-e, anti-C, anti-c, and anti-D) using the standard serologic technique.
RESULT
The most prevalent Rh antigen was "c" (98.5%), followed by "D" (97.7%), while the least was "C" (30.7%). The most prevalent phenotype was cDe/cDe (RR).
CONCLUSION
This work therefore concludes that the most prevalent rhesus antigen and rhesus phenotype was c and cDe/cDe among blood donors in University of Calabar Teaching Hospital.
背景
恒河猴抗原已被证实可导致新生儿溶血病以及急性和迟发性输血反应。本研究旨在评估所研究人群中恒河猴抗原（C、c、D、E和e）的频率。
方法
本研究为横断面研究，涉及130名前往卡拉巴尔大学教学医院（UCTH）献血门诊的潜在献血者。采用标准血清学技术将献血者按Rh抗血清（抗-E、抗-e、抗-C、抗-c和抗-D）分组。
结果
最常见的Rh抗原是“c”（98.5%），其次是“D”（97.7%），而最少见的是“C”（30.7%）。最常见的表型是cDe/cDe（RR）。
结论
因此，本研究得出结论，在卡拉巴尔大学教学医院的献血者中，最常见的恒河猴抗原和恒河猴表型分别是c和cDe/cDe。
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