Izumiyama Takuya, Mori Yu, Itoi Eiji
Department of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan.
Case Rep Rheumatol. 2020 Aug 24;2020:8899391. doi: 10.1155/2020/8899391. eCollection 2020.
Rheumatoid arthritis is characterized by multiple chronic arthritis subsequently inducing joint destruction. Although subchondral geode is a well-known feature of high-disease activity, a large geode is rare. Moreover, the treatment effect of biologic agents in the repair of large geode has not been reported. The present report shows the significant effect of interleukin-6 receptor blocker, tocilizumab, in repairing the large geode in the left humeral lateral epicondyle. This case implies that tocilizumab might be an effective treatment in patients with rheumatoid arthritis even with large geode.
类风湿性关节炎的特征是多发性慢性关节炎,随后会导致关节破坏。尽管软骨下结节是高疾病活动度的一个众所周知的特征,但大的结节很少见。此外,生物制剂在修复大结节方面的治疗效果尚未见报道。本报告显示,白细胞介素-6受体阻滞剂托珠单抗在修复左肱骨外侧髁的大结节方面具有显著效果。该病例表明,即使是患有大结节的类风湿性关节炎患者,托珠单抗也可能是一种有效的治疗方法。