Department of Gastroenterology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima, Japan.
Department of Endoscopy, Fukushima Medical University Hospital, 1 Hikarigaoka, Fukushima, Japan.
Clin J Gastroenterol. 2020 Dec;13(6):1051-1056. doi: 10.1007/s12328-020-01226-0. Epub 2020 Sep 9.
A 48-year-old man who underwent balloon dilation for esophageal achalasia more than 20 years prior developed severe dysphagia and cough during mealtimes. Endoscopic findings showed a markedly dilated esophagus with residue, narrowing of the esophagogastric junction (EGJ), and a fistula in the middle thoracic esophagus. Esophagography showed narrowing of the EGJ and outflow of contrast from the esophagus to the bronchus. In addition, computed tomography showed marked esophageal dilatation and diffuse granular shading in both lungs. Based on these imaging findings, the patient was diagnosed with deterioration of esophageal achalasia and an esophagobronchial fistula (EBF) secondary to achalasia. The increased intra-esophageal pressure caused by the achalasia was suspected to have inhibited the closure of the EBF. Therefore, we believed that per-oral endoscopic myotomy (POEM) would help treat the achalasia and simultaneously contribute to closing of the EBF. Immediately after POEM, the dysphagia and cough improved. Furthermore, the EBF was closed. 14 months after POEM, the patient did not exhibit deterioration of esophageal achalasia and EBF. To the best of our knowledge, there have been no reports of POEM implemented in cases of esophageal achalasia complicated by EBF. Therefore, this case is worth reporting.
一位 48 岁男性,20 多年前因食管失弛缓症接受了球囊扩张治疗,此后出现严重的吞咽困难和进餐时咳嗽。内镜检查发现食管明显扩张,有残留物,食管胃连接部(EGJ)变窄,中段食管有瘘管。食管造影显示 EGJ 狭窄,造影剂从食管流入支气管。此外,计算机断层扫描显示食管明显扩张,双肺弥漫性颗粒状阴影。根据这些影像学表现,该患者被诊断为食管失弛缓症恶化,并继发食管支气管瘘(EBF)。失弛缓症导致的食管内压增高,可能抑制了 EBF 的闭合。因此,我们认为经口内镜肌切开术(POEM)有助于治疗失弛缓症,并同时有助于闭合 EBF。POEM 后立即,吞咽困难和咳嗽改善。此外,EBF 闭合。POEM 后 14 个月,患者食管失弛缓症和 EBF 均未恶化。据我们所知,尚无 POEM 应用于食管失弛缓症并发 EBF 的报道。因此,值得报告这例病例。