Department of Anesthesiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Department of Neurosurgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Neuromodulation. 2021 Jun;24(4):763-768. doi: 10.1111/ner.13276. Epub 2020 Sep 9.
Dorsal root ganglion stimulation (DRGS) is an effective treatment for complex regional pain syndrome (CRPS) and post-surgical neuropathic pain. However, some patients have surgical and anatomical conditions that are contraindications to traditional DRGS technique. A novel transgrade approach to DRGS placement has been described and demonstrated effective for post spine surgery patients. We present three patients, each with a different reason in which DRGS would not be accessible via the traditional anterograde approach, who all had successful DRGS transgrade placement.
The case series includes three patients with either CRPS or post-surgical neuropathic pain who had an anatomical or post-surgical condition that historically would have rendered DRGS contraindicated. Two patients had previously failed dorsal column stimulation. All three patients had successful placement with the transgrade approach-entry into the contralateral epidural space at the level of the targeted foramen from a cephalad angle. Each patient gave their verbal and written consent to be included in the case series.
Following treatment with a transgrade approach, all three patients had significant pain relief and improvement in function without complication.
Barriers to anterograde foraminal access including previous implantation, previous instrumentation, and epidural adhesions may prevent DRGS placement in certain indicated patients. This can be especially challenging in patients who have failed other neuromodulation options like dorsal column stimulation. Our case series demonstrated that the transgrade technique can be successfully used in these cases to increase access to DRGS.
背根神经节刺激(DRGS)是治疗复杂性区域疼痛综合征(CRPS)和术后神经性疼痛的有效方法。然而,一些患者存在手术和解剖条件的限制,不适合传统的 DRGS 技术。一种新的逆行 DRGS 置管方法已被描述,并已证明对脊柱手术后患者有效。我们报告了 3 例患者,他们由于不同的原因,传统的顺行入路无法进行 DRGS,而这些患者均成功地进行了逆行 DRGS 置管。
该病例系列包括 3 例患有 CRPS 或术后神经性疼痛的患者,他们存在解剖或手术方面的情况,这些情况在历史上会使 DRGS 成为禁忌。其中 2 例患者之前曾行背柱刺激术失败。所有 3 例患者均采用逆行入路成功置管,即从颅侧角度进入对侧硬膜外腔,进入目标椎间孔的水平。每位患者均签署了口头和书面同意书,同意参与病例系列研究。
采用逆行入路治疗后,所有 3 例患者的疼痛均明显缓解,功能得到改善,且无并发症。
顺行入路的障碍,包括先前的植入物、先前的器械和硬膜外粘连,可能会使某些特定的患者无法进行 DRGS 置管。对于那些已经尝试过其他神经调节选择(如背柱刺激术)失败的患者,这可能会更加具有挑战性。我们的病例系列研究表明,逆行技术可以成功地用于这些病例,以增加 DRGS 的可及性。