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基于锚钉的股骨固定在保留骺板的内侧髌股韧带重建术中的应用:与肌腱固定螺钉固定的零时差生物力学比较。

Anchor-Based Femoral Fixation for Physeal-Sparing Medial Patellofemoral Ligament Reconstruction: A Time-Zero Biomechanical Comparison With Tenodesis Screw Fixation.

机构信息

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina, USA.

出版信息

Am J Sports Med. 2020 Oct;48(12):3021-3027. doi: 10.1177/0363546520951523. Epub 2020 Sep 10.

Abstract

BACKGROUND

Open physes and trochlear/notch geometries in pediatric patients limit the safe corridor for femoral interference screw graft fixation during medial patellofemoral ligament (MPFL) reconstruction. Accordingly, interest is increasing in anchor-based fixation, but biomechanical validation is deficient.

PURPOSE

To compare anchor-based and tenodesis screw femoral fixation of MPFL grafts in a time-zero biomechanical model.

STUDY DESIGN

Controlled laboratory study.

METHODS

Twenty-seven fresh-frozen porcine distal femurs were potted for testing in an electromechanical load frame, while bovine tendons were used for MPFL grafts. Reconstructions were performed with 1 of 3 femoral fixation strategies: 4.5-mm biocomposite double-loaded threaded anchor (DLA group), 3.9-mm biocomposite knotless threaded anchor (KA group), or traditional 7 × 23-mm biocomposite tenodesis screw (TS group). For testing, femoral specimens were oriented and secured in the mechanical testing apparatus such that actuator tensile pull re-created the normal MPFL trajectory. Specimens underwent 10 cycles of 5- to 15-N loading at 1-Hz preconditioning, followed by 1000 cycles of 10- to 50 N-loading at 1 Hz. After cyclic loading, all specimens were loaded to failure at 305 mm/min. The average cyclic construct stiffness, displacement, and load-to-failure data between the 3 groups were compared using analysis of variance (ANOVA) with the significance level set at < .05.

RESULTS

Average cyclic construct stiffnesses were comparable across groups per repeated-measures ANOVA analysis: 68.3 ± 6.3, 71.4 ± 6.4, and 74.3 ± 7.9 N/mm for TS, DLA, and KA groups, respectively (at cycle 1000). Average construct displacements at cycles 100 and 1000 were significantly less in the anchor versus tenodesis screw groups per ANOVA and Tukey post hoc analysis: 7.7 ± 4.2 mm for the TS group versus 3.7 ± 0.4 and 4.3 ± 0.6 mm for the DLA and KA groups, respectively (at cycle 1000). There was no significant difference in ultimate failure loads between the anchor and tenodesis screw groups, but 3 of 9 TS constructs failed at loads below the average failure load of the native MPFL.

CONCLUSION

Compared with the tenodesis group, anchor-based fixation produced constructs with equivalent cyclic stiffnesses, improved load-displacement characteristics, and had less failure load variability in the porcine cadaveric model.

CLINICAL RELEVANCE

Femoral fixation of the MPFL graft with a single anchor (4.5 or 3.9 mm threaded) is a viable alternative to traditional tenodesis screw fixation.

摘要

背景

在儿科患者中,开放性骨骺和滑车/切迹几何形状限制了内侧髌股韧带(MPFL)重建过程中股骨干扰螺钉移植物固定的安全通道。因此,人们对基于锚定的固定越来越感兴趣,但生物力学验证不足。

目的

在零时间生物力学模型中比较基于锚定和肌腱螺钉固定 MPFL 移植物的效果。

研究设计

对照实验室研究。

方法

将 27 个新鲜冷冻的猪股骨进行盆栽试验,置于机电负荷框架中,同时使用牛肌腱作为 MPFL 移植物。重建采用 3 种股骨固定策略之一:4.5mm 复合材料双载螺纹锚(DLA 组)、3.9mm 复合材料无结螺纹锚(KA 组)或传统的 7×23mm 复合材料肌腱螺钉(TS 组)。在测试过程中,股骨标本通过定向和固定在机械测试设备中,使驱动器的拉伸拉力重新创建正常的 MPFL 轨迹。标本在 1Hz 预处理下进行 10 个 5-15N 循环的预载,然后在 1Hz 下进行 1000 个 10-50N 循环的加载。循环加载后,所有标本均以 305mm/min 的速度加载至失效。使用方差分析(ANOVA)比较 3 组之间的平均循环构建刚度、位移和失效载荷数据,显著性水平设为<.05。

结果

重复测量 ANOVA 分析显示,各组的平均循环构建刚度相当:TS、DLA 和 KA 组分别为 68.3±6.3、71.4±6.4 和 74.3±7.9N/mm(循环 1000 次)。根据 ANOVA 和 Tukey 事后分析,在循环 100 和 1000 时,锚定组的结构位移明显小于肌腱螺钉组:TS 组为 7.7±4.2mm,DLA 和 KA 组分别为 3.7±0.4mm 和 4.3±0.6mm(循环 1000 次)。锚定组和肌腱螺钉组的最终失效载荷无显著差异,但 9 个 TS 结构中有 3 个在低于天然 MPFL 平均失效载荷的载荷下失效。

结论

与肌腱螺钉组相比,基于锚定的固定在猪尸体模型中产生了具有等效循环刚度、改善的载荷-位移特性的构建体,并且失效载荷的变异性更小。

临床相关性

MPFL 移植物的单锚定(4.5 或 3.9mm 螺纹)固定是传统肌腱螺钉固定的一种可行替代方法。

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