Miami University, Oxford, Ohio.
J Nerv Ment Dis. 2020 Nov;208(11):843-847. doi: 10.1097/NMD.0000000000001228.
Individuals with generalized anxiety disorder (GAD) report poorer quality of life (QOL) than do nonanxious controls. Further, although positive affect (PA) and negative affect (NA) have been shown to predict QOL, no previous literature has tested this relationship in the context of individuals with GAD. In the present study, we evaluated the unique and interactive contributions of PA and NA on QOL within a sample of individuals diagnosed with GAD (N = 50). Specifically, a hierarchical regression was conducted to evaluate the unique contributions of PA, NA, and their interaction on QOL, over and above symptoms of depression. PA and depression symptoms were both significant predictors of QOL, whereas neither the main effect for NA nor the PA × NA interaction was statistically significant. Results suggest that, for those with GAD, PA uniquely contributes to QOL. Strategies to upregulate PA may be a useful treatment target for increasing QOL in individuals with GAD.
广泛性焦虑障碍（GAD）患者的生活质量（QOL）比非焦虑对照者差。此外，尽管积极情绪（PA）和消极情绪（NA）已被证明可以预测 QOL，但以前的文献尚未在 GAD 患者的背景下测试这种关系。在本研究中，我们在一组被诊断为 GAD 的患者（N=50）中评估了 PA 和 NA 对 QOL 的独特和交互作用。具体来说，进行了层次回归分析，以评估 PA、NA 及其交互作用对 QOL 的独特贡献，超过了抑郁症状。PA 和抑郁症状都是 QOL 的重要预测因素，而 NA 的主效应和 PA×NA 交互作用都没有统计学意义。结果表明，对于那些患有 GAD 的人来说，PA 对 QOL 有独特的贡献。上调 PA 的策略可能是提高 GAD 患者 QOL 的有效治疗目标。
