Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Division of Cardiology, Duke University Medical Center, DUMC 3010, Durham, NC, 27710, USA.
Curr Cardiol Rep. 2020 Sep 10;22(11):136. doi: 10.1007/s11886-020-01389-9.
Adults with congenital heart disease (ACHD) are a rapidly growing population with ever-increasing complexity, and intensive care unit (ICU) management is often necessary. This review summarizes common cardiovascular and non-cardiovascular complications in ACHD and provides a framework for ICU care.
Heart failure is the leading cause of hospitalization and mortality in ACHD. Varied anatomy and repairs, as well as differing physiological complications, limit generalized application of management algorithms. Recent studies suggest that earlier mechanical support in advanced cases is feasible and potentially helpful. Cardiac arrhythmias are poorly tolerated and often require immediate attention. Other complications requiring intensive care include infections such as endocarditis and COVID-19, pulmonary hypertension, renal failure, hepatic dysfunction, coagulopathy, and stroke. Successful ICU care in ACHD requires a multi-disciplinary approach with careful consideration of anatomy, physiology, and associated comorbidities. Few studies have formally examined ICU management in ACHD and further research is necessary.
患有先天性心脏病(ACHD)的成年人是一个快速增长的群体,其复杂性不断增加,通常需要重症监护病房(ICU)的管理。本综述总结了 ACHD 常见的心血管和非心血管并发症,并为 ICU 护理提供了一个框架。
最新发现:心力衰竭是 ACHD 住院和死亡的主要原因。不同的解剖结构和修复方法,以及不同的生理并发症,限制了管理算法的广泛应用。最近的研究表明,在晚期病例中更早地使用机械支持是可行的,并且可能有帮助。心律失常耐受性差,通常需要立即关注。其他需要重症监护的并发症包括感染,如心内膜炎和 COVID-19、肺动脉高压、肾衰竭、肝功能障碍、凝血功能障碍和中风。在 ACHD 中成功进行 ICU 护理需要多学科方法,仔细考虑解剖结构、生理学和相关合并症。很少有研究对 ACHD 的 ICU 管理进行了正式研究,因此需要进一步研究。