Meschini Cesare, Cauteruccio Michele, Oliva Maria Serena, Sircana Giuseppe, Vitiello Raffaele, Rovere Giuseppe, Muratori Francesco, Maccauro Giulio, Ziranu Antonio
Department of Orthopedics, Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Università Cattolica del Sacro Cuore, Rome.
Department of Oncologic and Reconstructive Orthopedic Surgery, Azienda Ospedaliera Universitaria Careggi, Florence, Italy.
Orthop Rev (Pavia). 2020 Jun 26;12(Suppl 1):8687. doi: 10.4081/or.2020.8687. eCollection 2020 Jun 29.
Patients with alkaptonuria can present ochronotic degenerative arthropathy due to the accumulation of pigments in the cartilages. Ochronotic arthropathy initially affects the spine, then there is the involvement of the other large joints, with greater frequency of the knees. In this article we will present two patients with alkaptonuria who have been effectively treated with knee and hip replacement, comparing our experience with what is available in the literature.
患有尿黑酸尿症的患者可能会因软骨中色素的积累而出现褐黄病性退行性关节病。褐黄病性关节病最初影响脊柱，随后其他大关节也会受累，其中膝关节受累更为常见。在本文中，我们将介绍两名接受膝关节和髋关节置换术有效治疗的尿黑酸尿症患者，并将我们的经验与文献中的现有资料进行比较。
