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原发性肺癌(印戒细胞癌)中的危及生命的咯血

Life Threatening haemoptysis in primary lung cancer-signet ring cell carcinoma.

作者信息

Anwar Shamsuddin, Acharya Sudeep, Elsayegh Dany, Sokoloff Alisa, Rehan Maryam

机构信息

Staten Island University Hospital, Northwell Health, United States.

出版信息

Respir Med Case Rep. 2020 Aug 25;31:101195. doi: 10.1016/j.rmcr.2020.101195. eCollection 2020.

DOI:10.1016/j.rmcr.2020.101195
PMID:32913701
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7472919/
Abstract

Primary signet ring cell carcinoma of the lung is a rare non-small cell carcinoma of the lung with extremely aggressive features and poor prognosis. The diagnosis mainly required tissue biopsy with immunohistochemical analysis and gene mutation studies. We describe a unique case of primary signet ring cell carcinoma of the lung presenting with life threatening haemoptysis along with literature review of prognosis and management of this rare clinical entity.

摘要

原发性肺印戒细胞癌是一种罕见的非小细胞肺癌,具有极强的侵袭性且预后较差。诊断主要需要进行组织活检,并结合免疫组化分析和基因突变研究。我们描述了一例以危及生命的咯血为表现的原发性肺印戒细胞癌的独特病例,并对这种罕见临床实体的预后和治疗进行文献综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0af/7472919/87b294dde91b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0af/7472919/cbf6698950b5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0af/7472919/5cb4e170f5fb/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0af/7472919/87b294dde91b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0af/7472919/cbf6698950b5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0af/7472919/5cb4e170f5fb/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0af/7472919/87b294dde91b/gr3.jpg

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本文引用的文献

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Signet Ring Cell Carcinoma of the Lung: A Diagnostic Pitfall in Pregnancy.肺印戒细胞癌:妊娠中的诊断陷阱。
Case Rep Obstet Gynecol. 2019 Jun 12;2019:9461579. doi: 10.1155/2019/9461579. eCollection 2019.
2
New Era for Next-Generation Sequencing in Japan.日本下一代测序技术的新时代。
Cancers (Basel). 2019 May 28;11(6):742. doi: 10.3390/cancers11060742.
3
KRAS-mutant non-small cell lung cancer: Converging small molecules and immune checkpoint inhibition.KRAS 突变型非小细胞肺癌:小分子药物与免疫检查点抑制的融合。
基于机器学习的 Cox 比例风险模型预测肺印戒细胞癌的预后框架。
J Cancer Res Clin Oncol. 2024 Jul 25;150(7):364. doi: 10.1007/s00432-024-05886-0.
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Primary Lung Adenocarcinoma With ALK Gene Rearrangement Mostly Occupied by the Signet-Ring Cell Carcinoma Component: A Case Report.以印戒细胞癌成分为主的ALK基因重排原发性肺腺癌:一例报告
Cureus. 2023 Sep 11;15(9):e45068. doi: 10.7759/cureus.45068. eCollection 2023 Sep.
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A case report of primary signet ring cell carcinoma of the lung: imaging study and literature review.原发性肺印戒细胞癌病例报告:影像学研究及文献复习
Transl Lung Cancer Res. 2021 Sep;10(9):3840-3849. doi: 10.21037/tlcr-21-654.
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Primary signet-ring cell carcinoma of the lung in an HIV-positive patient.肺原发性印戒细胞癌合并 HIV 阳性患者。
Thorac Cancer. 2021 Apr;12(7):1122-1125. doi: 10.1111/1759-7714.13887. Epub 2021 Feb 16.
EBioMedicine. 2019 Mar;41:711-716. doi: 10.1016/j.ebiom.2019.02.049. Epub 2019 Mar 7.
4
Survival in signet ring cell carcinoma varies based on primary tumor location: a Surveillance, Epidemiology, and End Results database analysis.印戒细胞癌的生存情况因原发肿瘤部位而异:一项监测、流行病学和最终结果数据库分析。
Expert Rev Gastroenterol Hepatol. 2018 Feb;12(2):209-214. doi: 10.1080/17474124.2018.1416291. Epub 2017 Dec 17.
5
Primary signet-ring cell carcinoma of the lung treated with crizotinib: A case report.克唑替尼治疗原发性肺印戒细胞癌:一例报告
Oncol Lett. 2015 May;9(5):2205-2207. doi: 10.3892/ol.2015.3003. Epub 2015 Mar 2.
6
Pulmonary adenocarcinoma with signet ring cell features: a comprehensive study from 3 distinct patient cohorts.具有印戒细胞特征的肺腺癌:来自3个不同患者队列的综合研究
Am J Surg Pathol. 2014 Dec;38(12):1681-8. doi: 10.1097/PAS.0000000000000280.
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Int J Clin Exp Pathol. 2012;5(2):171-4. Epub 2012 Feb 12.
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