Wu Cheng-Chun, Huang Faye, Hsieh Ching-Hua, Fu Chih-Pin, Tsai Yi-Lin, Lai Jui-Pin
Department of Plastic Surgery, 63328Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung.
Cleft Palate Craniofac J. 2021 Apr;58(4):407-413. doi: 10.1177/1055665620954085. Epub 2020 Sep 11.
This study was designed to identify the potential predictors of postoperative velopharyngeal function after double opposing Z-plasty (DOZP) for the treatment of velopharyngeal insufficiency (VPI) in patients who had prior palatoplasty for cleft palate.
This retrospective study reviewed the medical records of consecutive patients who received DOZP for VPI after receiving a prior palatoplasty treating cleft palate between 2004 and 2017. The speech outcome of patient was measured using the Pittsburgh Weighted Speech Scale (PWSS) at 6 months following surgery and determined the outcome suggests velopharyngeal competence (PWSS ≤2) or incompetence (PWSS >2). Stepwise logistic regression was used to identify the variables for the prediction of competent surgical outcome. The specific receiver operating characteristic curves with an area under the curve (AUC) was used to evaluate the predictor related to the surgical outcome as competence.
The study included 93 patients. Age, relative velar length, velar lengthening, and closure pattern were not significantly associated with postoperative competence status of the patient. The only variable that predicted a successful surgical outcome was preoperative velar closing ratio. However, the accuracy of velar closing ratio in predicting a competent surgical outcome is only moderate (AUC = 70.37).
The results of this study showed that preoperative velar closing ratio may predict, with moderate accuracy, a successful surgical outcome in patients with postpalatoplasty VPI who undergo DOZP. Therefore, in patients with a low preoperative velar closing ratio, some alternative surgical methods other than DOZP may be considered to avoid unsatisfactory surgical outcome.
本研究旨在确定在曾接受腭裂修复术的患者中,采用双侧反向 Z 形瓣术(DOZP)治疗腭咽闭合不全(VPI)后腭咽功能的潜在预测因素。
这项回顾性研究回顾了 2004 年至 2017 年间因 VPI 接受 DOZP 手术且此前已接受腭裂修复术的连续患者的病历。在术后 6 个月使用匹兹堡加权语音量表(PWSS)测量患者的语音结果,并确定结果表明腭咽功能正常(PWSS≤2)或功能不全(PWSS>2)。采用逐步逻辑回归确定预测手术成功结果的变量。使用具有曲线下面积(AUC)的特定受试者工作特征曲线来评估与手术结果为功能正常相关的预测因素。
该研究纳入了 93 名患者。年龄、相对软腭长度、软腭延长和闭合模式与患者术后的功能状态无显著相关性。唯一能预测手术成功结果的变量是术前软腭闭合率。然而,软腭闭合率预测手术成功结果的准确性仅为中等(AUC = 70.37)。
本研究结果表明,术前软腭闭合率可能以中等准确性预测接受 DOZP 的腭裂修复术后 VPI 患者的手术成功结果。因此,对于术前软腭闭合率较低的患者,可考虑采用 DOZP 以外的其他替代手术方法,以避免手术结果不理想。