• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

腭咽闭合率作为腭裂患者腭裂修复术后腭咽功能不全行双反向Z成形术后腭咽功能的预测指标。

Velar Closing Ratio As a Predictor for the Verlopharyngeal Function After Double Opposing Z-Plasty for Postpalatoplasty Velopharyngeal Insufficiency in Patients With Cleft Palate.

作者信息

Wu Cheng-Chun, Huang Faye, Hsieh Ching-Hua, Fu Chih-Pin, Tsai Yi-Lin, Lai Jui-Pin

机构信息

Department of Plastic Surgery, 63328Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung.

出版信息

Cleft Palate Craniofac J. 2021 Apr;58(4):407-413. doi: 10.1177/1055665620954085. Epub 2020 Sep 11.

DOI:10.1177/1055665620954085
PMID:32914636
Abstract

BACKGROUND

This study was designed to identify the potential predictors of postoperative velopharyngeal function after double opposing Z-plasty (DOZP) for the treatment of velopharyngeal insufficiency (VPI) in patients who had prior palatoplasty for cleft palate.

METHODS

This retrospective study reviewed the medical records of consecutive patients who received DOZP for VPI after receiving a prior palatoplasty treating cleft palate between 2004 and 2017. The speech outcome of patient was measured using the Pittsburgh Weighted Speech Scale (PWSS) at 6 months following surgery and determined the outcome suggests velopharyngeal competence (PWSS ≤2) or incompetence (PWSS >2). Stepwise logistic regression was used to identify the variables for the prediction of competent surgical outcome. The specific receiver operating characteristic curves with an area under the curve (AUC) was used to evaluate the predictor related to the surgical outcome as competence.

RESULTS

The study included 93 patients. Age, relative velar length, velar lengthening, and closure pattern were not significantly associated with postoperative competence status of the patient. The only variable that predicted a successful surgical outcome was preoperative velar closing ratio. However, the accuracy of velar closing ratio in predicting a competent surgical outcome is only moderate (AUC = 70.37).

CONCLUSION

The results of this study showed that preoperative velar closing ratio may predict, with moderate accuracy, a successful surgical outcome in patients with postpalatoplasty VPI who undergo DOZP. Therefore, in patients with a low preoperative velar closing ratio, some alternative surgical methods other than DOZP may be considered to avoid unsatisfactory surgical outcome.

摘要

背景

本研究旨在确定在曾接受腭裂修复术的患者中,采用双侧反向 Z 形瓣术(DOZP)治疗腭咽闭合不全(VPI)后腭咽功能的潜在预测因素。

方法

这项回顾性研究回顾了 2004 年至 2017 年间因 VPI 接受 DOZP 手术且此前已接受腭裂修复术的连续患者的病历。在术后 6 个月使用匹兹堡加权语音量表(PWSS)测量患者的语音结果,并确定结果表明腭咽功能正常(PWSS≤2)或功能不全(PWSS>2)。采用逐步逻辑回归确定预测手术成功结果的变量。使用具有曲线下面积(AUC)的特定受试者工作特征曲线来评估与手术结果为功能正常相关的预测因素。

结果

该研究纳入了 93 名患者。年龄、相对软腭长度、软腭延长和闭合模式与患者术后的功能状态无显著相关性。唯一能预测手术成功结果的变量是术前软腭闭合率。然而,软腭闭合率预测手术成功结果的准确性仅为中等(AUC = 70.37)。

结论

本研究结果表明,术前软腭闭合率可能以中等准确性预测接受 DOZP 的腭裂修复术后 VPI 患者的手术成功结果。因此,对于术前软腭闭合率较低的患者,可考虑采用 DOZP 以外的其他替代手术方法,以避免手术结果不理想。

相似文献

1
Velar Closing Ratio As a Predictor for the Verlopharyngeal Function After Double Opposing Z-Plasty for Postpalatoplasty Velopharyngeal Insufficiency in Patients With Cleft Palate.腭咽闭合率作为腭裂患者腭裂修复术后腭咽功能不全行双反向Z成形术后腭咽功能的预测指标。
Cleft Palate Craniofac J. 2021 Apr;58(4):407-413. doi: 10.1177/1055665620954085. Epub 2020 Sep 11.
2
Age and Preoperative Velar Closure Ratio Are Significantly Associated With Surgical Outcome of Furlow Double-Opposing Z-Plasty in Palatal Re-Repair.年龄和术前腭帆闭合率与腭裂再次修复中Furlow双反向Z成形术的手术结果显著相关。
J Oral Maxillofac Surg. 2020 Mar;78(3):431-439. doi: 10.1016/j.joms.2019.09.023. Epub 2019 Sep 27.
3
Radiographic and aerodynamic measures of velopharyngeal anatomy and function following Furlow Z-plasty.Furlow Z形瓣术后腭咽解剖结构与功能的影像学及空气动力学测量
Plast Reconstr Surg. 2000 Sep;106(3):539-49; discussion 550-3.
4
A modified procedure for velopharyngeal sphincteroplasty in primary cleft palate repair and secondary velopharyngeal incompetence treatment and its preliminary results.一种改良的腭咽括约肌成形术在原发性腭裂修复及继发性腭咽功能不全治疗中的应用及其初步结果。
J Plast Reconstr Aesthet Surg. 2006;59(8):817-25. doi: 10.1016/j.bjps.2005.11.006. Epub 2006 Feb 2.
5
Single vs. Double-Opposing Z-Plasty: Evaluating Their Impact on Palatoplasty Postoperative Outcomes.单 Z 成形术与双反对 Z 成形术在腭裂术后效果的比较。
Clin Oral Investig. 2024 Jul 11;28(8):422. doi: 10.1007/s00784-024-05818-9.
6
Lateral pharyngeal wall and velar movement and tailoring velopharyngeal surgery: determinants of velopharyngeal incompetence resolution in patients with cleft palate.咽侧壁和软腭运动与腭咽成形手术的调整:腭裂患者腭咽功能不全解决的决定因素
Plast Reconstr Surg. 2007 Aug;120(2):495-505. doi: 10.1097/01.prs.0000267438.18295.e4.
7
Use of a modified Furlow Z-plasty as a secondary cleft palate repair procedure to reduce velopharyngeal insufficiency.使用改良的Furlow Z形瓣成形术作为二期腭裂修复手术以减少腭咽闭合不全。
Int J Oral Maxillofac Surg. 2016 Feb;45(2):170-6. doi: 10.1016/j.ijom.2015.07.006. Epub 2015 Aug 5.
8
Proposed clinical model for predicting speech outcomes in patients undergoing Furlow palatoplasty for velopharyngeal insufficiency after primary palatoplasty.初次腭裂修复术后行 Furlow 腭裂修复术治疗伴发咽腔闭合不全患者的语音结局预测临床模型的建立。
J Craniomaxillofac Surg. 2024 Feb;52(2):234-239. doi: 10.1016/j.jcms.2023.12.007. Epub 2023 Dec 16.
9
Redo double-opposing Z-plasty is effective for correction of marginal velopharyngeal insufficiency.再次进行双侧反向 Z 成形术对纠正边缘性腭咽闭合不全有效。
J Plast Reconstr Aesthet Surg. 2015 Sep;68(9):1215-20. doi: 10.1016/j.bjps.2015.05.014. Epub 2015 Jun 4.
10
Double-Opposing Z-Palatoplasty for Secondary Surgical Management of Velopharyngeal Incompetence in the Absence of a Primary Furlow Palatoplasty.在未进行初次Furlow腭成形术的情况下,采用双反向Z形腭成形术对腭咽闭合不全进行二次手术治疗。
Cleft Palate Craniofac J. 2015 Sep;52(5):517-24. doi: 10.1597/13-187. Epub 2014 Sep 22.

引用本文的文献

1
Effectiveness of secondary furlow palatoplasty with buccal myomucosal flap in correction of velopharyngeal insufficiency in patients with cleft palate.二次颊黏膜瓣 Furlow 腭裂修补术治疗腭裂患者伴发的咽腔闭合不全的疗效。
Clin Oral Investig. 2024 Apr 17;28(5):257. doi: 10.1007/s00784-024-05607-4.
2
Preoperative Velopharyngeal Closure Predicts Hypernasality Outcomes of Secondary Furlow Double-Opposing Z-Plasty.术前腭咽闭合情况可预测二期Furlow双反向Z成形术的鼻音过重结局。
Cleft Palate Craniofac J. 2025 Jun;62(6):1023-1031. doi: 10.1177/10556656241237422. Epub 2024 Mar 14.
3
How Early Can We Predict the Need for VPI Surgery?
我们能多早预测腭裂修复手术的需求?
Plast Reconstr Surg Glob Open. 2022 Nov 21;10(11):e4678. doi: 10.1097/GOX.0000000000004678. eCollection 2022 Nov.