Pascual-Castroviejo I
Service of Child Neurology, Hospital Infantil La Paz, Madrid.
Brain Dev. 1988;10(2):84-7. doi: 10.1016/s0387-7604(88)80076-7.
Intoxication caused by adulterated rapeseed oil was observed in Madrid (Spain) and adjacent areas in the spring of 1981. The toxic syndrome affected about 25,000 people. Thereafter a multisystemic disease developed that has caused about 600 deaths and 300 invalids. Although almost all organs of the body are affected, the peripheral nervous system shows the most severe alterations. Today, seven years after the onset of the disease, nothing is yet known about the etiopathogenesis or the nature of the causative agent.
1981年春，在西班牙马德里及周边地区发现了由掺假菜籽油导致的中毒事件。中毒综合征影响了约2.5万人。此后发展出一种多系统疾病，已造成约600人死亡和300人残疾。尽管身体几乎所有器官都受到影响，但外周神经系统的改变最为严重。如今，该病发病七年之后，其病因发病机制或致病因子的性质仍一无所知。
