Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Malaya, Kuala Lumpur Malaysia.
Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Cancer Prev Res (Phila). 2021 Jan;14(1):105-112. doi: 10.1158/1940-6207.CAPR-20-0280. Epub 2020 Sep 11.
Vaginal self-sampling for human papillomavirus (HPV) testing can potentially increase cervical screening coverage. This study aimed to investigate the acceptability of vaginal self-sampling for HPV testing and factors that might influence a woman's preference for this as a cervical screening method. This was a cross-sectional study that recruited 725 women from the urban and suburban areas of Selangor, Malaysia. All study participants were instructed to self-collect vaginal sample using a dry flocked swab before responding to a detailed questionnaire documenting their experience and preference for self-sampling. Most of the study participants (>80%) perceived vaginal self-sampling as easy, convenient, not embarrassing, comfortable, and were confident in performing the test. This suggests high acceptability toward vaginal self-sampling for HPV testing. Of the 725 women, 83% preferred self-sampling HPV testing over healthcare personnel sampling HPV testing and Pap test. Women with higher household income and full-time employment status were more likely to prefer self-sampling. Those who had not undergone Pap test also expressed preference for self-sampling HPV testing. Convenience and women's confidence in performing a vaginal self-sampling for HPV testing were the independent key factors that influenced the preference for self-sampling method. Vaginal self-sampling for HPV testing is highly acceptable among Malaysian women. It is the preferred choice as a primary cervical screening method and serves as an alternative to healthcare-acquired sample for Pap test. PREVENTION RELEVANCE: Organized cervical cancer screening remains unachievable in many countries. Self-sampling HPV testing is an evidence-based method that can remove barriers to cervical screening. This is particularly important for developing countries in order to achieve the WHO global strategy to accelerate cervical cancer elimination.
人乳头瘤病毒（HPV）检测的阴道自我采样可能会增加子宫颈筛查的覆盖率。本研究旨在调查 HPV 检测阴道自我采样的可接受性，以及可能影响女性对这种子宫颈筛查方法偏好的因素。这是一项横断面研究，在马来西亚雪兰莪州的城乡地区招募了 725 名女性。所有研究参与者都被指示使用干式纤维拭子自行采集阴道样本，然后回答详细的问卷，记录他们对自我采样的经验和偏好。大多数研究参与者（>80%）认为阴道自我采样简单、方便、不尴尬、舒适，并对进行这项检测有信心。这表明 HPV 检测的阴道自我采样具有很高的可接受性。在 725 名女性中，83%的人更喜欢自我采样 HPV 检测，而不是医护人员采样 HPV 检测和巴氏涂片检查。家庭收入较高和全职工作的女性更倾向于自我采样。那些没有做过巴氏涂片检查的人也表示更喜欢自我采样 HPV 检测。方便和女性对自我进行 HPV 检测的阴道采样的信心是影响自我采样方法偏好的独立关键因素。马来西亚女性对 HPV 检测的阴道自我采样具有很高的可接受性。它是首选的子宫颈筛查方法，也是巴氏涂片检查中获取医护人员样本的替代方法。预防相关性：在许多国家，有组织的子宫颈癌筛查仍然无法实现。自我采样 HPV 检测是一种基于证据的方法，可以消除子宫颈筛查的障碍。对于发展中国家来说，这一点尤为重要，因为它们需要实现世卫组织加速消除子宫颈癌的全球战略。
