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一种用于同时测量腕部脉压和心脏电活动的碳纳米管-聚二甲基硅氧烷可穿戴设备。

A CNT-PDMS wearable device for simultaneous measurement of wrist pulse pressure and cardiac electrical activity.

作者信息

Wang Li, Dou Wenkun, Chen Jun, Lu Kechao, Zhang Feng, Abdulaziz Mohammed, Su Weiguang, Li Anqing, Xu Chonghai, Sun Yu

机构信息

Advanced Micro and Nanoinstruments Center (AMNC), School of Mechanical & Automotive Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, Shandong 250353, China.

Department of Mechanical and Industrial Engineering, University of Toronto, Toronto, ON M5S 3G8, Canada.

出版信息

Mater Sci Eng C Mater Biol Appl. 2020 Dec;117:111345. doi: 10.1016/j.msec.2020.111345. Epub 2020 Aug 11.

DOI:10.1016/j.msec.2020.111345
PMID:32919692
Abstract

Simultaneous measurement of multi-physiological signals can provide effective diagnosis and therapeutic assessment of diseases. This paper reports a carbon nanotube (CNT) - Polydimethylsiloxane (PDMS) - based wearable device with piezo-resistive and voltage-sensing capabilities for simultaneously capturing wrist pulse pressure and cardiac electrical signal. The layout design of sensing elements in the device was guided by analyzing strain distribution and electric field distribution for minimizing the interference between wrist pulse and cardiac electric activity during measurement. Each device was preconditioned under the strain of 20% until the resistance change of the device reached equilibrium. After preconditioning, the relationship between the resistance change and the pressure was calibrated, which determined the device sensitivity to be 0.01 Pa and the linear pressure range of the device to be 0.4 kPa to 14.0 kPa. Mechanisms of CNT-PDMS for sensing strain signal and electrical pulse signal were explored by scanning electron microscopy (SEM) imaging and equivalent circuit modeling. The device was applied to monitor the wrist pulse and ECG signals of volunteers during the recovering process after physical exercises.

摘要

同时测量多种生理信号可以为疾病提供有效的诊断和治疗评估。本文报道了一种基于碳纳米管(CNT)-聚二甲基硅氧烷(PDMS)的可穿戴设备,该设备具有压阻和电压传感功能,可同时采集手腕脉搏压力和心脏电信号。通过分析应变分布和电场分布来指导设备中传感元件的布局设计,以在测量过程中最小化手腕脉搏和心脏电活动之间的干扰。每个设备在20%的应变下进行预处理,直到设备的电阻变化达到平衡。预处理后,校准了电阻变化与压力之间的关系,确定设备灵敏度为0.01 Pa,设备的线性压力范围为0.4 kPa至14.0 kPa。通过扫描电子显微镜(SEM)成像和等效电路建模探索了CNT-PDMS传感应变信号和电脉冲信号的机制。该设备应用于监测志愿者体育锻炼后恢复过程中的手腕脉搏和心电图信号。

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