Department of Intensive Care, School of Wenzhou Medical University, Wenzhou, China.
Department of Intensive Care, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Ann Palliat Med. 2020 Sep;9(5):3522-3527. doi: 10.21037/apm-19-284. Epub 2020 Sep 5.
The mortality of acute respiratory distress syndrome (ARDS) remains high, and mechanical ventilation (MV) is an essential means of treatment. During MV, people realize the benefits of spontaneous breathing and the disadvantages of uncontrolled spontaneous breathing. Current methods of monitoring spontaneous breathing include oesophageal manometry, P0.1, and diaphragm function monitoring. However, these methods have limitations and deficiencies. The driving pressure is a new indicator that reflects the strain of the lung, which indicates the volumetric injury of the lung and is independently associated with mortality in ARDS patients. Moreover, in recent studies, driving pressure monitoring has been shown to be feasible in assisted support ventilation. This review summarizes the current state of spontaneous breathing and examines whether it is convenient to monitor driving pressure during spontaneous breathing to achieve lung protection ventilation.
急性呼吸窘迫综合征(ARDS)的死亡率仍然很高,机械通气(MV)是治疗的重要手段。在 MV 过程中,人们认识到自主呼吸的好处和不受控制的自主呼吸的缺点。目前监测自主呼吸的方法包括食管测压、P0.1 和膈肌功能监测。然而,这些方法有其局限性和不足。驱动压是一种反映肺应变的新指标,它提示肺容积损伤,与 ARDS 患者的死亡率独立相关。此外,在最近的研究中,驱动压监测在辅助支持通气中显示是可行的。本综述总结了自主呼吸的现状,并探讨了在自主呼吸期间监测驱动压是否方便,以实现肺保护性通气。