Department of Otolaryngology-Head and Neck Surgery, The Second Xiangya Hospital, 12570Central South University, Changsha, Hunan, People's Republic of China.
Department of Head and Neck Surgery, National Cancer Center/National Clinical Research Center for Cancer/ Cancer Hospital & Shenzhen Hospital, 12501Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, Guangdong, People's Republic of China.
Ear Nose Throat J. 2022 Jun;101(5):NP203-NP208. doi: 10.1177/0145561320953696. Epub 2020 Sep 14.
This study presents a case of Extraosseous Ewing sarcoma arising in the cervical esophagus of a 36-year-old woman who presented with cervical mass and dysphagia. Imaging studies demonstrated a well-defined, cystic-solid mass in the neck extending into the upper mediastinum, which results in deviation of the trachea and esophagus. The relationship between the tumor and the cervical esophagus was found in the operation. The patient underwent localized tumor resection without radical esophagectomy. The accurate diagnosis was obtained by the immunohistochemistry and molecular genetic assay. Although this is a rare site for this type of tumor to occur, extraosseous Ewing sarcoma should be considered in the differential diagnosis of small round cell tumors of the cervical esophagus. The postoperative chemotherapy and radiotherapy are of great value in improving the prognosis of cervical esophageal Ewing sarcoma.
本研究报道了一例发生于 36 岁女性颈段食管的骨外尤文肉瘤,患者表现为颈部长肿块和吞咽困难。影像学检查显示颈部有一个界限清楚的囊性实性肿块,延伸至上纵隔,导致气管和食管移位。术中发现肿瘤与颈段食管的关系。患者接受了局部肿瘤切除术,而非根治性食管切除术。通过免疫组织化学和分子遗传学检测获得了准确的诊断。尽管这种类型的肿瘤在这个部位很少见,但在颈段食管小圆细胞肿瘤的鉴别诊断中应考虑到骨外尤文肉瘤。颈段食管尤文肉瘤的术后化疗和放疗对改善预后具有重要价值。