Martini R B, Peralta Soler A, Gil O A, Valenzuela C, Schneider A, Luna J
Université Nationale de Cordoba, Unité de Chirurgie Expérimentale de l'Hôpital Italien-Cordoba, R. Argentine.
J Chir (Paris). 1988 Apr;125(4):264-9.
Nineteen of twenty dogs undergoing experimental esophageal transection with mechanical suturing were followed up over 1 to 120 days by means of light and electron microscopy examinations to evaluate changes in suture line. Histology showed few reactions to the metallic clips, the absence of new vessel formation with early healing from the 4th day, development of collagen fascicles after 1 week and consolidation after 2 weeks with reparation by the end of 1st month. Stability of healing process was apparent between 3 and 4 months, without evidence of stenosis due to scar tissue.
对20只接受机械缝合的实验性食管横断术的犬中的19只进行了1至120天的随访,通过光学显微镜和电子显微镜检查来评估缝线处的变化。组织学显示对金属夹的反应很少,从第4天开始早期愈合时没有新血管形成,1周后胶原束开始发育,2周后巩固,在第1个月末实现修复。愈合过程在3至4个月时明显稳定,没有因瘢痕组织导致狭窄的迹象。