Orlov V A, Gitel' E P
Probl Endokrinol (Mosk). 1977 May-Jun;23(3):24-9.
The serum content of immunoreactive insulin and growth hormone was determined during the intravenous glucose tolerance test in 104 patients suffering from chronic pancreatitis at the stage of exacerbation and of clinical remission. Reduction of glucose tolerance was more pronounced during the exacerbation of the disease than at the period of clinical remission. In comparison with the control group, insulin hypersecretion (more pronounced during the exacerbation) was revealed in these groups of patients as a whole. A reduction of the insulin/glucose ratio in the patients indicated a relative character of insulin deficiency. The maximal reduction of the insulin/glucose ratio was noted in the patients with a diabetic character of glucose tolerance. Elevation of the growth hormone basal secretion in comparison with control was revealed in the patients at the period of exacerbation.
在104例处于病情加重期和临床缓解期的慢性胰腺炎患者进行静脉葡萄糖耐量试验期间，测定了免疫反应性胰岛素和生长激素的血清含量。疾病加重期葡萄糖耐量降低比临床缓解期更明显。与对照组相比，这些患者组总体上显示出胰岛素分泌过多（在病情加重期更明显）。患者胰岛素/葡萄糖比值降低表明存在相对性胰岛素缺乏。葡萄糖耐量呈糖尿病特征的患者胰岛素/葡萄糖比值降低最为明显。病情加重期患者的生长激素基础分泌与对照组相比有所升高。
