[四氧嘧啶对两栖类胰腺胰岛器作用的超微结构分析]
[Ultrastructural analysis of the effect of alloxan on the insular apparatus of the pancreas in amphibia].
作者信息
Iaglov V V
出版信息
Probl Endokrinol (Mosk). 1977 May-Jun;23(3):87-9.
PMID:329271
Abstract
Administration of alloxan to Rana temporaria in a dose of 300 mg/kg caused a complex of reactive changes in the pancreas (degranulation of B-cells, of acino-islar cells of B type, and of the exocrine pancreocytes; edema of the secretory granules, lysosome activation, disturbance of the secretory cycle course), which were irreversible in the majority of cells.
摘要
以300毫克/千克的剂量给林蛙注射四氧嘧啶，会引起胰腺一系列反应性变化（B细胞、B型腺泡胰岛细胞和胰腺外分泌细胞脱颗粒；分泌颗粒水肿、溶酶体激活、分泌周期进程紊乱），这些变化在大多数细胞中是不可逆的。
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