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COVID-19 大流行期间婴儿痉挛症的管理:南亚婴儿痉挛症研究组的观点。

Management of West syndrome during COVID-19 pandemic: A viewpoint from South Asian West Syndrome Research Group.

机构信息

Pediatric Neurology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Pediatric Neurology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Epilepsy Res. 2020 Nov;167:106453. doi: 10.1016/j.eplepsyres.2020.106453. Epub 2020 Aug 31.

Abstract

In the wake of the pandemic COVID-19 and nationwide lockdowns gripping many countries globally, the national healthcare systems are either overwhelmed or preparing to combat this pandemic. Despite all the containment measures in place, experts opine that this novel coronavirus is here to stay as a pandemic or an endemic. Hence, it is apt to be prepared for the confrontation and its aftermath. From protecting the vulnerable individuals to providing quality care for all health conditions and maintaining essential drug supplies, it is going to be a grueling voyage. Preparedness to sustain optimal care for each health condition is a must. With a higher risk for severe COVID-19 disease in infants, need of high-dose hormonal therapy with a concern of consequent severe disease, presence of comorbidities, and a need for frequent investigations and follow-up; children with West syndrome constitute a distinctive group with special concerns. In this viewpoint, we discuss the important issues and concerns related to the management of West syndrome during COVID-19 pandemic in the South Asian context and provide potential solutions to these concerns based on the current evidence, adeptness, and consensus. Some plausible solutions include the continuation of containment and mitigation measures for COVID-19, therapeutic decision- making for West syndrome based on risk stratification, and tele-epileptology.

摘要

在 COVID-19 大流行和全球许多国家实施全国性封锁之后,国家医疗保健系统要么不堪重负,要么准备应对这一大流行病。尽管采取了所有遏制措施,专家们认为这种新型冠状病毒将作为大流行或地方病继续存在。因此,做好应对准备及其后果是恰当的。从保护弱势群体到为所有健康状况提供优质护理以及维持基本药物供应,这将是一场艰苦的航行。必须为维持每一种健康状况的最佳护理做好准备。由于婴儿患严重 COVID-19 疾病的风险较高,需要高剂量的激素治疗,并担心随之而来的严重疾病,存在合并症,以及需要频繁的检查和随访;患有 West 综合征的儿童构成了一个具有特殊关注点的独特群体。在这篇观点文章中,我们讨论了与南亚背景下 COVID-19 大流行期间 West 综合征管理相关的重要问题和关注点,并根据当前的证据、专业知识和共识为这些关注点提供了潜在的解决方案。一些可行的解决方案包括继续采取 COVID-19 的遏制和缓解措施、基于风险分层的 West 综合征治疗决策以及远程癫痫学。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c62/7456842/b738c48a357d/gr1_lrg.jpg

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