Darbà Josep, Marsà Alicia
Department of Economics, Universitat De Barcelona, Barcelona, Spain.
Department of Health Economics, BCN Health Economics & Outcomes Research S.L. Travessera De Gràcia, Barcelona, Spain.
Expert Rev Pharmacoecon Outcomes Res. 2021 Oct;21(5):1101-1106. doi: 10.1080/14737167.2020.1820328. Epub 2020 Sep 14.
Alzheimer's disease (AD) is the most common form of dementia. Its neurodegenerative nature and the lack of a curative treatment result in a substantial burden for healthcare systems and society. This study aimed to analyze the hospital incidence and mortality of AD in Spain and to evaluate patients' use of healthcare resources and direct medical costs.
Admission records of patients with AD treated in hospitals in Spain between 2011 and 2016 were selected from a Spanish hospital discharge database.
Records of 7,894 patients with diagnosed AD were analyzed. Hospital incidence was 3.7 per 10,000 persons over the study period, 2.9 and 4.4 for males and females, respectively. In-hospital mortality was 9.5%; both hospital incidence and in-hospital mortality increased over the study period. Mortality was principally associated with acute respiratory failure and other diseases of the respiratory system and heart failure. Annual medical costs of specialized care increased slightly during the study period, with a mean annual cost per patient of €4,969.
AD is responsible for an increasing proportion of hospitalizations in Spain and raising medical costs, which highlights the importance of early detection and optimized care.
阿尔茨海默病（AD）是最常见的痴呆形式。其神经退行性本质以及缺乏治愈性治疗给医疗系统和社会带来了沉重负担。本研究旨在分析西班牙AD的医院发病率和死亡率，并评估患者对医疗资源的使用情况及直接医疗费用。
从西班牙医院出院数据库中选取2011年至2016年在西班牙医院接受治疗的AD患者的入院记录。
分析了7894例确诊为AD患者的记录。在研究期间，医院发病率为每10000人中有3.7例，男性和女性分别为2.9例和4.4例。住院死亡率为9.5%；在研究期间，医院发病率和住院死亡率均有所上升。死亡率主要与急性呼吸衰竭、呼吸系统其他疾病和心力衰竭有关。在研究期间，专科护理的年度医疗费用略有增加，每位患者的平均年度费用为4969欧元。
在西班牙，AD导致住院的比例不断增加，医疗费用不断上升，这凸显了早期检测和优化护理的重要性。
