Departamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad Universitaria, Ciudad de México, México.
Int J Dev Biol. 2021;65(1-2-3):143-152. doi: 10.1387/ijdb.200220jc.
Cell fusion is a process in which cells unite their membranes and cytoplasm. It is fundamental for sexual reproduction and embryonic development. Among the best-known cell fusion processes during animal development are fertilization, myoblast fusion, osteoclast generation, and vulva formation in . Although it is involved in many other functions in unicellular and multicellular organisms, little is known about the mechanisms of cell fusion and the genes that code for the proteins participating in this process. Benjamin Podbilewicz has dedicated many years to understanding the processes and mechanisms of cell fusion. In this interview, he spoke to us about how he began his studies of this process, his contributions to this exciting field, his scientific ties with Ibero-America and his strategies for a well-balanced scientific/personal life.
细胞融合是细胞融合其细胞膜和细胞质的过程。它是有性生殖和胚胎发育的基础。在动物发育过程中,最著名的细胞融合过程包括受精、成肌细胞融合、破骨细胞生成和. 尽管它在单细胞和多细胞生物的许多其他功能中都有涉及,但对于细胞融合的机制以及参与该过程的蛋白质的编码基因知之甚少。本杰明·波比莱维茨(Benjamin Podbilewicz)多年来一直致力于了解细胞融合的过程和机制。在这次采访中,他向我们讲述了他是如何开始研究这个过程的,他对这个令人兴奋的领域的贡献,他与伊比利亚-美洲的科学联系以及他平衡科学/个人生活的策略。