粪便标本中 SARS-CoV-2 无症状感染儿童长期 RT-PCR 阳性的随访研究。
Follow-up Study of Long-time Positive RT-PCR in Stool Specimens From Asymptomatic Children Infected With SARS-CoV-2.
机构信息
From the Department of Respiratory Medicine.
National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders.
出版信息
Pediatr Infect Dis J. 2020 Oct;39(10):e315-e317. doi: 10.1097/INF.0000000000002837.
In the current study, we report on 4 children with confirmed SARS-CoV-2 infection, of which 3 of them were asymptomatic. These patients had both pharyngeal swabs and anal swabs testing during hospital or after discharge. All the 4 children showed long-time positive viral RNA in the stool specimens after pharyngeal swabs turned negative during the follow-up stage, especially in the asymptomatic children. The positive RNA in stool specimens of asymptomatic children last for more than 54 days after admission or 30 days after discharge.
在本研究中，我们报告了 4 例确诊的 SARS-CoV-2 感染患儿，其中 3 例为无症状感染者。这些患儿在住院期间或出院后均进行了咽拭子和肛拭子检测。在随访阶段，所有 4 例患儿在咽拭子转为阴性后，粪便标本中均持续长时间检出病毒 RNA，尤其是在无症状患儿中。无症状患儿粪便标本中阳性 RNA 在上呼吸道感染后 54 天以上或出院后 30 天以上仍可检出。
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