Zhao H T, Peng Z B, Yang X K, Li Z L, Ren M R, Qin Y, Sun X J, Yu J X, An Z J, Mao N Y, Xu W W, Li Z J
Division of Infectious Disease, Key Laboratory of Infectious Disease Surveillance and Early-warning, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Branch of Respiratory Disease, Division of Infectious Disease, Key Laboratory of Infectious Disease Surveillance and Ear-warning, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2021 Jan 10;42(1):39-43. doi: 10.3760/cma.j.cn112338-20200809-01047.
COVID-19 is an emerging infectious disease caused by SARS-CoV-2. After the infection of the virus, the host immune system is stimulated to produce multifarious specific antibodies to decrease or eliminate effects of the pathogen. Study of the specific antibodies dynamic characteristics in patients with COVID-19 is very important for the understanding and diagnosis of the disease, research and development of vaccine, and planning of prevention and control strategy. This paper reviews and summarizes the domestic and oversea research on dynamic characteristics of specific antibodies of COVID-19 patients, including the antibody producing, duration and level, and its possible influencing factors in order to improve the understanding of the immunological characteristics of COVID-19.
新型冠状病毒肺炎（COVID-19）是由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的一种新发传染病。病毒感染后，宿主免疫系统受到刺激，产生多种特异性抗体以降低或消除病原体的影响。研究新型冠状病毒肺炎患者特异性抗体的动态特征对于疾病的认识与诊断、疫苗研发以及防控策略的制定都非常重要。本文综述并总结了国内外关于新型冠状病毒肺炎患者特异性抗体动态特征的研究，包括抗体产生、持续时间和水平及其可能的影响因素，以增进对新型冠状病毒肺炎免疫特征的了解。
