State Key Laboratory of Food Science and Technology, Nanchang University, No. 235 Nanjing East Road, Nanchang 330047, China.
School of Life Sciences, Nanchang University, Nanchang 330031, China.
Molecules. 2020 Sep 12;25(18):4188. doi: 10.3390/molecules25184188.
β-carotene is a promising natural active ingredient for optimum human health. However, the insolubility in water, low oral bioavailability, and instability in oxygen, heat, and light are key factors to limit its application as incorporation into functional foods. Therefore, gliadin nanoparticles (GNPs) Pickering emulgels were chosen as food-grade β-carotene delivery systems. The objectives of the present study were to investigate the influence of GNPs concentration on the rheological properties, stability, and simulated gastrointestinal fate of β-carotene of Pickering emulgels. The formulations of Pickering emulgels at low GNPs concentration had better fluidity, whereas at high GNPs concentration, they had stronger gel structures. Furthermore, the thermal stability of β-carotene loaded in Pickering emulgels after two pasteurization treatments was significantly improved with the increase of GNPs concentration. The Pickering emulgels stabilized with higher GNPs concentration could improve the protection and bioaccessibility of β-carotene after different storage conditions. This study demonstrated the tremendous potential of GNPs Pickering emulgels to carry β-carotene.
β-胡萝卜素是一种很有前途的天然活性成分，可促进人体健康。然而，β-胡萝卜素在水中的不溶性、低口服生物利用度以及对氧气、热和光的不稳定性，是限制其作为功能性食品添加剂应用的关键因素。因此，选择麦醇溶蛋白纳米粒子（GNPs）作为 Pickering 乳剂来作为食品级β-胡萝卜素的递送系统。本研究的目的是研究 GNPs 浓度对 Pickering 乳剂中β-胡萝卜素的流变特性、稳定性和模拟胃肠道命运的影响。低浓度 GNPs 的 Pickering 乳剂具有更好的流动性，而高浓度 GNPs 的 Pickering 乳剂具有更强的凝胶结构。此外，随着 GNPs 浓度的增加，经两次巴氏杀菌处理后，负载β-胡萝卜素的 Pickering 乳剂的热稳定性显著提高。用较高浓度 GNPs 稳定的 Pickering 乳剂可以改善β-胡萝卜素在不同储存条件下的保护和生物利用度。本研究表明，GNPs Pickering 乳剂在携带β-胡萝卜素方面具有巨大的潜力。
