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氟溴马唑仑的滑坡效应:瑞典一个在线论坛上对一种新型精神活性苯二氮䓬类药物的讨论

The slippery slope of flubromazolam: Experiences of a novel psychoactive benzodiazepine as discussed on a Swedish online forum.

作者信息

Andersson Martin, Kjellgren Anette

机构信息

Karlstad University, Sweden.

出版信息

Nordisk Alkohol Nark. 2017 Jun;34(3):217-229. doi: 10.1177/1455072517706304. Epub 2017 May 16.

Abstract

AIM

The purpose of this qualitative study was to investigate the effects experienced by users of a novel psychoactive substance, the benzodiazepine flubromazolam, by analysing users' own accounts on the Swedish forum Flashback.org.

METHOD

A thematic analysis of anonymous self-reports published on the forum was performed and generated five general themes describing effects and experiences by flubromazolam users.

RESULTS

The themes which emerged were: Onset and duration, Desired effects, Adverse effects and addiction, Loss of control, General estimations and evaluations. The main reported characteristics of flubromazolam were heavy hypnotic and sedative effects, long-lasting amnesiac effects and the rapid development of tolerance. Flubromazolam was also anxiolytic and acted as a muscle relaxant for many users. Some users experienced euphoria or intense wellbeing. Other prominent characteristics were loss of control (leading to poor choices and actions, with unpleasant consequences) and long-lasting, often severe withdrawals. There were also serious incidents where users had been admitted to hospital, acute psychiatric treatment or taken into custody by the police.

CONCLUSION

Flubromazolam appears to be a highly addictive and precarious benzodiazepine with many, possibly severe, side effects. The substance is generally described as very potent and with long-lasting effects. Memory loss and loss of control are common adverse effects, and withdrawals appear to be severe for many users.

摘要

目的

这项定性研究的目的是通过分析瑞典论坛Flashback.org上用户的自述,调查新型精神活性物质氟溴唑仑使用者所经历的影响。

方法

对论坛上发布的匿名自我报告进行主题分析,得出五个描述氟溴唑仑使用者的影响和体验的一般主题。

结果

出现的主题有:起效和持续时间、预期效果、不良反应和成瘾、失控、总体估计和评价。氟溴唑仑报告的主要特征是强烈的催眠和镇静作用、持久的失忆作用以及耐受性的快速发展。对许多使用者来说,氟溴唑仑还具有抗焦虑作用并可作为肌肉松弛剂。一些使用者体验到欣快感或强烈的幸福感。其他突出特征是失控(导致做出糟糕的选择和行为,并产生不愉快的后果)以及持久且往往严重的戒断反应。还有一些严重事件,使用者被送进医院、接受急性精神科治疗或被警方拘留。

结论

氟溴唑仑似乎是一种极易成瘾且危险的苯二氮䓬类药物,有许多可能严重的副作用。该物质通常被描述为效力很强且作用持久。记忆丧失和失控是常见的不良反应,对许多使用者来说戒断反应似乎很严重。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b5c/7450873/78f9ace0cc2d/10.1177_1455072517706304-fig1.jpg

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