Ince Nevin, Güçlü Ertuğrul, Sungur Mehmet Ali, Karabay Oğuz
. Department of Infectious Diseases and Clinical Microbiology, Duzce University Faculty of Medicine, Duzce, Turkey.
. Sakarya University Medical Faculty Teaching and Research Hospital Infectious Diseases and Clinical Microbiology Department, Sakarya, Turkey.
Rev Assoc Med Bras (1992). 2020 Aug;66(8):1077-1081. doi: 10.1590/1806-9282.66.8.1077.
Cellulite infection is a non-necrotizing inflammation of the skin and subcutaneous tissue and is one of the most common reasons for admission to hospital. This retrospective study aimed to investigate the Neutrophil to Lymphocyte Ratio (NLR), Platelet to Lymphocyte Ratio (PLR), and Lymphocyte to Monocyte Ratio (LMR) in patients with cellulitis.
In our study, we retrospectively analyzed 96 patients with cellulitis and 98 age- and sex-matched healthy controls. The study and control groups were compared regarding NLR, PLR, and LMR.0.001). When patients with cellulitis were divided into two groups, i.e., ≥65 years and <65 years, a statistically significant difference was noted in the NLR and LMR values (p < 0.05). In the ROC curve analysis, NLR had the highest discriminative power in distinguishing between cellulitis and healthy controls (AUC = 0.950, 95% CI: 0.920-0.979, p < 0.001; 91.6% sensitivity and 89.8% specificity).
NLR was significantly higher in differentiating cellulite and in patients older than 65 years. Larger, prospective studies are required to determine its usefulness in assessing differential diagnosis and prognosis in cellulitis patients.
蜂窝织炎感染是皮肤和皮下组织的一种非坏死性炎症，是住院的最常见原因之一。这项回顾性研究旨在调查蜂窝织炎患者的中性粒细胞与淋巴细胞比值（NLR）、血小板与淋巴细胞比值（PLR）和淋巴细胞与单核细胞比值（LMR）。
在我们的研究中，我们回顾性分析了96例蜂窝织炎患者和98例年龄及性别匹配的健康对照。比较了研究组和对照组的NLR、PLR和LMR。0.001）。当将蜂窝织炎患者分为两组，即≥65岁和<65岁时，NLR和LMR值存在统计学显著差异（p<0.05）。在ROC曲线分析中，NLR在区分蜂窝织炎和健康对照方面具有最高的判别能力（AUC = 0.950，95%CI：0.920 - 0.979，p<0.001；敏感性为91.6%，特异性为89.8%）。
NLR在区分蜂窝织炎和65岁以上患者中显著更高。需要开展更大规模的前瞻性研究来确定其在评估蜂窝织炎患者鉴别诊断和预后方面的有用性。
