Devita Robert, Chagarlamudi Kaushik, Kardan Arash
Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
World J Nucl Med. 2020 Jan 17;19(2):144-146. doi: 10.4103/wjnm.WJNM_63_19. eCollection 2020 Apr-Jun.
Tc-99m methylene diphosphonate bone scintigraphy (bone scan) is a highly sensitive technique for the evaluation of osseous pathology. However, the nonspecificity of the method can present diagnostic challenges in differentiating benign from malignant processes. Often, Paget's disease and osseous metastasis can coexist in elderly patients. Therefore, it is important to accurately distinguish the two pathologies, as each has a different prognosis and impacts clinical management. Obtaining the appropriate clinical diagnosis often involves a combination of laboratory, radiographic, and clinical data. We present a case of newly diagnosed prostatic carcinoma presenting with synchronous osseous metastasis, degenerative changes, and incidental multifocal Paget's disease.
锝-99m亚甲基二膦酸盐骨闪烁显像(骨扫描)是评估骨病变的一种高度敏感的技术。然而,该方法的非特异性在区分良性与恶性病变时可能带来诊断挑战。在老年患者中,佩吉特病和骨转移常常并存。因此,准确区分这两种病变很重要,因为它们各自有着不同的预后并影响临床管理。获得恰当的临床诊断通常需要结合实验室、影像学和临床数据。我们报告一例新诊断的前列腺癌病例,该病例同时存在骨转移、退行性改变和偶然发现的多灶性佩吉特病。