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一名骨髓移植受者因吸食受污染大麻而患致命性曲霉病。

Fatal aspergillosis associated with smoking contaminated marijuana, in a marrow transplant recipient.

作者信息

Hamadeh R, Ardehali A, Locksley R M, York M K

机构信息

Department of Medicine, University of California San Francisco Medical Center.

出版信息

Chest. 1988 Aug;94(2):432-3. doi: 10.1378/chest.94.2.432.

DOI:10.1378/chest.94.2.432
PMID:3293934
Abstract

A 34-year-old man presented with pulmonary aspergillosis on the 75th day after marrow transplant for chronic myelogenous leukemia. The patient had smoked marijuana heavily for several weeks prior to admission. Cultures of the marijuana revealed Aspergillus fumigatus with morphology and growth characteristics identical to the organism grown from open lung biopsy specimen. Despite aggressive antifungal therapy, the patient died with disseminated disease. Physicians should be aware of this potentially lethal complication of marijuana use in compromised hosts.

摘要

一名34岁男性在接受慢性粒细胞白血病骨髓移植术后第75天出现肺曲霉病。该患者在入院前数周大量吸食大麻。对大麻的培养显示烟曲霉,其形态和生长特征与从开放性肺活检标本中培养出的微生物相同。尽管进行了积极的抗真菌治疗,患者仍死于播散性疾病。医生应意识到在免疫功能低下宿主中使用大麻可能导致这种潜在致命的并发症。

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